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Discovery of soluble epoxide hydrolase inhibitors from chemical synthesis and natural products
CP Sun, XY Zhang, C Morisseau… - Journal of medicinal …, 2020 - ACS Publications
Soluble epoxide hydrolase (sEH) is an α/β hydrolase fold protein and widely distributed in
numerous organs including the liver, kidney, and brain. The inhibition of sEH can effectively …
numerous organs including the liver, kidney, and brain. The inhibition of sEH can effectively …
Structures and bioactive properties of myrtucommulones and related acylphloroglucinols from Myrtaceae
Myrtaceae are a group of plants that include a number of renowned species used in
ethnomedicine in many areas worldwide. Their valuable therapeutic properties have …
ethnomedicine in many areas worldwide. Their valuable therapeutic properties have …
Discovery of glycosidated glycyrrhetinic acid derivatives: Natural product-based soluble epoxide hydrolase inhibitors
Q Liu, YX Wang, ZH Ge, MZ Zhu, J Ding… - European Journal of …, 2024 - Elsevier
There are few reports on soluble epoxide hydrolase (sEH) structure-activity relationship
studies using natural product-based scaffolds. In this study, we discovered that C-30 urea …
studies using natural product-based scaffolds. In this study, we discovered that C-30 urea …
Highly Potent Antiausterity Agents from Callistemon citrinus and Their Mechanism of Action against the PANC-1 Human Pancreatic Cancer Cell Line
AM Tawila, S Sun, MJ Kim, AM Omar… - Journal of Natural …, 2020 - ACS Publications
Human pancreatic cancer cells display remarkable tolerance to nutrition starvation that help
them to survive in a hypovascular tumor microenvironment, a phenomenon known as …
them to survive in a hypovascular tumor microenvironment, a phenomenon known as …
Chemical constituents of Callistemon citrinus from Egypt and their antiausterity activity against PANC-1 human pancreatic cancer cell line
Human pancreatic cancer is resistant to almost all conventional chemotherapeutic agents. It
is known to proliferate aggressively within hypovascular tumor microenvironment by …
is known to proliferate aggressively within hypovascular tumor microenvironment by …
Establishment of pressurized-liquid extraction by response surface methodology approach coupled to HPLC-DAD-TOF-MS for the determination of phenolic …
Myrtus communis L.(myrtle) is native to the Mediterranean region and Western Asia. Its
leaves have demonstrated its potential effect towards different bioactivities like anti-diabetic …
leaves have demonstrated its potential effect towards different bioactivities like anti-diabetic …
Kaempferia diterpenoids and flavonoids: an overview on phytochemistry, biosynthesis, synthesis, pharmacology, and pharmacokinetics
Kaempferia species have contained various crucial ethnobotanical features, and are being
used as traditional folk medicines in some Southeast Asia. This review tends to highlight …
used as traditional folk medicines in some Southeast Asia. This review tends to highlight …
Callistemon genus- a review on phytochemistry and biological activities
Callistemon is an important genus in the family Myrtaceae which contains about 34 species.
The members of this genus are known for their ornamental potentials, in addition to their …
The members of this genus are known for their ornamental potentials, in addition to their …
Acylphloroglucinols from the leaves of Callistemon viminalis
A phytochemical study on the leaves of Callistemon viminalis, a widely distributed
ornamental and medicinal plant of agricultural importance in China, resulted in the isolation …
ornamental and medicinal plant of agricultural importance in China, resulted in the isolation …
Antiplasmodial β-Triketone–Flavanone Hybrids from the Flowers of the Australian Tree Corymbia torelliana
The methanol extract of the flowers of the Australian eucalypt tree Corymbia torelliana
yielded six new β-triketone–flavanone hybrids, torellianones A–F (1–6), the …
yielded six new β-triketone–flavanone hybrids, torellianones A–F (1–6), the …