Energy decomposition analysis

L Zhao, M von Hopffgarten… - Wiley …, 2018 - Wiley Online Library
The energy decomposition analysis (EDA) is a powerful method for a quantitative
interpretation of chemical bonds in terms of three major components. The instantaneous …

Anomeric effect, hyperconjugation and electrostatics: Lessons from complexity in a classic stereoelectronic phenomenon

IV Alabugin, L Kuhn, NV Krivoshchapov… - Chemical Society …, 2021 - pubs.rsc.org
Understanding the interplay of multiple components (steric, electrostatic, stereoelectronic,
dispersive, etc.) that define the overall energy, structure, and reactivity of organic molecules …

Cation− π interaction: Its role and relevance in chemistry, biology, and material science

AS Mahadevi, GN Sastry - Chemical reviews, 2013 - ACS Publications
Noncovalent interactions are essential for the existence of solid and liquid phases. 1, 2
Traditionally touted as weak forces, quantification of these interactions, which govern the …

Quantifying aromaticity with electron delocalisation measures

F Feixas, E Matito, J Poater, M Solà - Chemical Society Reviews, 2015 - pubs.rsc.org
Aromaticity cannot be measured directly by any physical or chemical experiment because it
is not a well-defined magnitude. Its quantification is done indirectly from the measure of …

Cycloaddition reactivities analyzed by energy decomposition analyses and the frontier molecular orbital model

A Sengupta, B Li, D Svatunek, F Liu… - Accounts of Chemical …, 2022 - ACS Publications
Conspectus This Account describes our quest to understand and predict organic reactivity, a
principal goal of physical and theoretical organic chemistry. The focus is on the development …

Nucleus-independent chemical shifts (NICS) as an aromaticity criterion

Z Chen, CS Wannere, C Corminboeuf, R Puchta… - Chemical …, 2005 - ACS Publications
Few concepts are as frequently used as aromaticity in the current chemical literature. 1 This
may be quantified by ca. 300 000 papers dealing with the aromatic properties of chemical …

Energy decomposition analysis approaches and their evaluation on prototypical protein–drug interaction patterns

MJS Phipps, T Fox, CS Tautermann… - Chemical society …, 2015 - pubs.rsc.org
The partitioning of the energy in ab initio quantum mechanical calculations into its chemical
origins (eg, electrostatics, exchange–repulsion, polarization, and charge transfer) is a …

Quantum mechanical methods for enzyme kinetics

J Gao, DG Truhlar - Annual Review of Physical Chemistry, 2002 - annualreviews.org
▪ Abstract This review discusses methods for the incorporation of quantum mechanical
effects into enzyme kinetics simulations in which the enzyme is an explicit part of the model …

On the nature of the halogen bond

C Wang, D Danovich, Y Mo, S Shaik - Journal of chemical theory …, 2014 - ACS Publications
The wide-ranging applications of the halogen bond (X-bond), notably in self-assembling
materials and medicinal chemistry, have placed this weak intermolecular interaction in a …

Ring currents

P Lazzeretti - Progress in nuclear magnetic resonance spectroscopy, 2000 - Elsevier
Proposed more than 60 years ago, the ring current model (RCM) is still widely used to
rationalize the peculiar magnetic properties of aromatic molecules at the turn of the century …