Novel perspective for protein–drug interaction analysis: atomic force microscope
H Sun, J Wang - Analyst, 2023 - pubs.rsc.org
Proteins are major drug targets, and drug–target interaction identification and analysis are
important factors for drug discovery. Atomic force microscopy (AFM) is a powerful tool …
important factors for drug discovery. Atomic force microscopy (AFM) is a powerful tool …
How E-, L-, and P-Selectins Bind to sLex and PSGL-1: A Quantification of Critical Residue Interactions
Selectins and their ability to interact with specific ligands are a cornerstone in cell
communication. Over the last three decades, a considerable wealth of experimental and …
communication. Over the last three decades, a considerable wealth of experimental and …
CD34+ HSPCs-derived exosomes contain dynamic cargo and promote their migration through functional binding with the homing receptor E-selectin
Exosomes are tiny vesicles released by cells that carry communications to local and distant
locations. Emerging research has revealed the role played by integrins found on the surface …
locations. Emerging research has revealed the role played by integrins found on the surface …
Single-molecule scale quantification reveals interactions underlying protein–protein interface: from forces to non-covalent bonds
H Sun, Y Tian, Y Fu, Y Lei, Y Wang, X Yan… - Physical Chemistry …, 2023 - pubs.rsc.org
Protein–protein interactions (PPIs) between the B-cell lymphoma 2 (Bcl-2) family are
considered a major driving force in cell cycle regulation and signaling. However, how this …
considered a major driving force in cell cycle regulation and signaling. However, how this …
[HTML][HTML] Analogues of the pan-selectin antagonist rivipansel (GMI-1070)
The selectin family consisting of E−, P-and L-selectin plays dominant roles in
atherosclerosis, ischemia-reperfusion injury, inflammatory diseases, and metastatic …
atherosclerosis, ischemia-reperfusion injury, inflammatory diseases, and metastatic …
[HTML][HTML] Single-Molecule-Level Quantification Based on Atomic Force Microscopy Data Reveals the Interaction between Melittin and Lipopolysaccharide in Gram …
S Huang, G Su, L Yang, L Yue, L Chen… - International Journal of …, 2024 - mdpi.com
The interaction forces and mechanical properties of the interaction between melittin (Mel)
and lipopolysaccharide (LPS) are considered to be crucial driving forces for Mel when killing …
and lipopolysaccharide (LPS) are considered to be crucial driving forces for Mel when killing …
Molecular-Scale Investigations Reveal the Effect of Natural Polyphenols on BAX/Bcl-2 Interactions
H Sun, F Liao, Y Tian, Y Lei, Y Fu, J Wang - International Journal of …, 2024 - mdpi.com
Apoptosis signaling controls the cell cycle through the protein–protein interactions (PPIs) of
its major B-cell lymphoma 2-associated x protein (BAX) and B-cell lymphoma 2 protein (Bcl …
its major B-cell lymphoma 2-associated x protein (BAX) and B-cell lymphoma 2 protein (Bcl …
Retention of E-selectin functionalized liposome Fanny packs on Jurkat cells following invasion through collagen
Circulating immune cells are an appealing candidate to serve as carriers of therapeutic
cargo via nanoparticles conjugated to their surface, for several reasons: these cells are …
cargo via nanoparticles conjugated to their surface, for several reasons: these cells are …
[PDF][PDF] Single− molecule Level Quantification Reveals the Interaction between Melittin and Lipopolysaccharide by Atomic Force Microscopy
S Huang, G Su, L Yang, L Yue, L Chen, J Huang… - 2024 - preprints.org
The interaction forces and mechanical properties of the interaction between melittin (Mel)
and lipopolysaccharide (LPS) are considered a crucial driving force for Mel in killing Gram …
and lipopolysaccharide (LPS) are considered a crucial driving force for Mel in killing Gram …