Circulating cell-free DNA enables noninvasive diagnosis of heart transplant rejection
Monitoring allograft health is an important component of posttransplant therapy.
Endomyocardial biopsy is the current gold standard for cardiac allograft monitoring but is an …
Endomyocardial biopsy is the current gold standard for cardiac allograft monitoring but is an …
Temporal response of the human virome to immunosuppression and antiviral therapy
I De Vlaminck, KK Khush, C Strehl, B Kohli, H Luikart… - Cell, 2013 - cell.com
There are few substantive methods to measure the health of the immune system, and the
connection between immune strength and the viral component of the microbiome is poorly …
connection between immune strength and the viral component of the microbiome is poorly …
Liquid biopsies to monitor solid organ transplant function: a review of new biomarkers
JGHP Verhoeven, K Boer… - Therapeutic drug …, 2018 - journals.lww.com
Despite modern immunosuppressive therapy, allograft rejection remains a major cause of
solid organ transplant dysfunction. For clinical care, organ transplant function is routinely …
solid organ transplant dysfunction. For clinical care, organ transplant function is routinely …
Cardiovascular magnetic resonance for rejection surveillance after cardiac transplantation
Background: Endomyocardial biopsy (EMB) is the gold standard method for surveillance of
acute cardiac allograft rejection (ACAR) despite its invasive nature. Cardiovascular …
acute cardiac allograft rejection (ACAR) despite its invasive nature. Cardiovascular …
Advances in diagnostics for transplant rejection
Introduction: Identification of allograft injury, including acute clinical and subclinical injury, is
vital in increasing the longevity of the transplanted organ. Acute rejection, which occurs as a …
vital in increasing the longevity of the transplanted organ. Acute rejection, which occurs as a …
[HTML][HTML] Cardiovascular magnetic resonance in heart transplant patients: diagnostic value of quantitative tissue markers: T2 map** and extracellular volume fraction …
E Vermes, CΩ PantalΩon, A Auvet… - Journal of …, 2018 - Elsevier
Background The diagnosis of acute rejection in cardiac transplant recipients requires
invasive technique with endomyocardial biopsy (EMB) which has risks and limitations …
invasive technique with endomyocardial biopsy (EMB) which has risks and limitations …
Serum exosomal protein profiling for the non-invasive detection of cardiac allograft rejection
PJ Kennel, A Saha, DA Maldonado, R Givens… - The Journal of Heart and …, 2018 - Elsevier
Background Exosomes are cell-derived circulating vesicles that play an important role in cell–
cell communication. Exosomes are actively assembled and carry messenger RNAs …
cell communication. Exosomes are actively assembled and carry messenger RNAs …
Randomized pilot trial of gene expression profiling versus heart biopsy in the first year after heart transplant: early invasive monitoring attenuation through gene …
J Kobashigawa, J Patel, B Azarbal… - Circulation: Heart …, 2015 - Am Heart Assoc
Background—The endomyocardial biopsy (EMB) is considered the gold standard in
rejection surveillance post cardiac transplant, but is invasive, with risk of complications. A …
rejection surveillance post cardiac transplant, but is invasive, with risk of complications. A …
Safety of right and left ventricular endomyocardial biopsy in heart transplantation and cardiomyopathy patients
Background Endomyocardial biopsy (EMB) facilitates a histopathologic diagnosis with
unique prognostic and therapeutic implications in both native and donor hearts. It is a …
unique prognostic and therapeutic implications in both native and donor hearts. It is a …
Point-of-care non-invasive enzyme-cleavable nanosensors for acute transplant rejection detection
Accurate and non-invasive monitoring of allograft posttransplant is essential for early
detection of acute cellular rejection and determines the long-term survival of the graft …
detection of acute cellular rejection and determines the long-term survival of the graft …