[HTML][HTML] Targeted Chiral Metabolomics of D-Amino Acids: Their Emerging Role as Potential Biomarkers in Neurological Diseases with a Focus on Their Liquid …

C Lella, L Nestor, D De Bundel… - International Journal of …, 2024 - mdpi.com
In neuroscience research, chiral metabolomics is an emerging field, in which D-amino acids
play an important role as potential biomarkers for neurological diseases. The targeted chiral …

[HTML][HTML] Dopamine‑iron homeostasis interaction rescues mitochondrial fitness in Parkinson's disease

C Buoso, M Seifert, M Lang, CM Griffith… - Neurobiology of …, 2024 - Elsevier
Imbalances of iron and dopamine metabolism along with mitochondrial dysfunction have
been linked to the pathogenesis of Parkinson's disease (PD). We have previously suggested …

[HTML][HTML] Blood D-serine levels correlate with aging and dopaminergic treatment in Parkinson's disease

A Imarisio, I Yahyavi, M Avenali, A Di Maio… - Neurobiology of …, 2024 - Elsevier
We recently described increased D-and L-serine concentrations in the striatum of 1-methyl-4-
phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-treated monkeys, the post-mortem caudate …

Serum dysregulation of serine and glycine metabolism as predictive biomarker for cognitive decline in frail elderly subjects

A Imarisio, I Yahyavi, C Gasparri, A Hassan… - Translational …, 2024 - nature.com
Frailty is a common age-related clinical syndrome characterized by a decline in the function
of multiple organ systems, increased vulnerability to stressors, and a huge socio-economic …

[HTML][HTML] Positive relation between dopamine neuron degeneration and metabolic connectivity disruption in the MPTP plus probenecid mouse model of Parkinson's …

MT Mazzocco, M Serra, M Maspero, A Coliva… - Experimental …, 2024 - Elsevier
The clinical manifestation of Parkinson's disease (PD) appears when neurodegeneration is
already advanced, compromising the efficacy of disease-modifying treatment approaches …

Extract from Nasco pomace loaded in nutriosomes exerts anti-inflammatory effects in the MPTP mouse model of Parkinson's disease

P Parekh, M Serra, M Allaw, M Perra, A Pinna… - Experimental …, 2024 - Elsevier
Neuroinflammation has recently emerged as a key event in Parkinson's disease (PD)
pathophysiology and as a potential target for disease-modifying therapies. Plant-derived …

Ezrin-mediated astrocyte-synapse signaling regulates cognitive function via astrocyte morphological changes in fine processes in male mice

L Chen, J Jiao, F Lei, B Zhou, H Li, P Liao, X Li… - Brain, Behavior, and …, 2025 - Elsevier
Astrocytes, which actively participate in cognitive processes, have a complex spongiform
morphology, highlighted by extensive ramified fine processes that closely enwrap the pre …

Serum D-serine to total serine ratio and glycine levels as predictive biomarkers for cognitive dysfunction in frail elderly subjects

A Imarisio, I Yahyavi, C Gasparri, A Hassan, M Avenali… - 2024 - researchsquare.com
Frailty is a common age-related clinical syndrome characterized by a decline in the function
of multiple organ systems, increased vulnerability to stressors and huge socio-economic …

[PDF][PDF] Serum dysregulation of serine and glycine metabolism as predictive biomarker for cognitive decline in frail elderly

A Imarisio, I Yahyavi, C Gasparri, A Hassan, M Avenali… - 2024 - researchgate.net
Frailty is a complex clinical syndrome characterized by a progressive deterioration of
physiological function of multiple organ systems, with consequent increased vulnerability to …