The mechanisms behind the Warburg effect in mammalian cells, as well as for the similar
Crabtree effect in the yeast Saccharomyces cerevisiae, are still a matter of debate: why do …

Simple Summary Cancer can be considered the epidemic of the third millennium, and recent
projections paint a worrying scenario for the coming decades. Knowledge about the causes …

A bioactive synthetic porous shell was engineered to enable cells to survive in an
oligotrophic environment. Eukaryotic cells (yeast) were firstly coated with a β‐galactosidase …

Quantification of metabolites is of pivotal relevance in biology, where it complements more
established omics techniques such as transcriptomics and proteomics. Here, we present a …

One of the key ways in which microbes are thought to regulate their metabolism is by
modulating the availability of enzymes through transcriptional regulation. However, the …

To elucidate the role of Cu and Fe NPs on the yield of wheat varieties, a gel-free proteomic
technique was used. NPs were synthesized and characterized through zeta potential, EDX …

Background Many details in cell culture-derived influenza vaccine production are still poorly
understood and approaches for process optimization mainly remain empirical. More insights …

Although transplantation of single genes in yeast plays a key role in elucidating gene
functionality in metazoans, technical challenges hamper humanization of full pathways and …

Supply of Gibbs free energy and precursors are vital for cellular function and cell metabolism
have evolved to be tightly regulated to balance their supply and consumption. Precursors …

What is the relationship between enzymes and metabolites, the two major constituents of
metabolic networks? We propose three alternative relationships between enzyme capacity …