Scleral structure and biomechanics

C Boote, IA Sigal, R Grytz, Y Hua, TD Nguyen… - Progress in retinal and …, 2020 - Elsevier
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …

Indirect traumatic optic neuropathy

EL Singman, N Daphalapurkar, H White… - Military Medical …, 2016 - Springer
Indirect traumatic optic neuropathy (ITON) refers to optic nerve injury resulting from impact
remote to the optic nerve. The mechanism of injury is not understood, and there are no …

[HTML][HTML] Finite element analysis predicts large optic nerve head strains during horizontal eye movements

X Wang, H Rumpel, WEH Lim… - … & visual science, 2016 - jov.arvojournals.org
Purpose: We combined finite element (FE) analysis and dynamic magnetic resonance
imaging (MRI) to estimate optic nerve head (ONH) strains during horizontal eye movements …

[HTML][HTML] Optic nerve sheath as a novel mechanical load on the globe in ocular duction

JL Demer - Investigative ophthalmology & visual science, 2016 - arvojournals.org
Purpose: The optic nerve (ON) sheath's role in limiting duction has been previously
unappreciated. This study employed magnetic resonance imaging (MRI) to demonstrate this …

Glaucoma-related changes in the mechanical properties and collagen micro-architecture of the human sclera

B Coudrillier, JK Pijanka, JL Jefferys, A Goel… - PloS one, 2015 - journals.plos.org
Objective The biomechanical behavior of the sclera determines the level of mechanical
insult from intraocular pressure to the axons and tissues of the optic nerve head, as is of …

A prospective longitudinal study to investigate corneal hysteresis as a risk factor for predicting development of glaucoma

CN Susanna, A Diniz-Filho, FB Daga… - American journal of …, 2018 - Elsevier
Purpose To investigate the role of corneal hysteresis (CH) as a risk factor for development of
glaucoma. Design Prospective observational cohort study. Methods Two hundred and eighty …

Collagen architecture of the posterior pole: high-resolution wide field of view visualization and analysis using polarized light microscopy

NJ Jan, K Lathrop, IA Sigal - Investigative ophthalmology & …, 2017 - iovs.arvojournals.org
Purpose: The purpose of this study was to leverage polarized light microscopy (PLM) to
visualize the collagen fiber architecture of posterior pole and optic nerve head with …

[HTML][HTML] Finite element modeling of factors influencing optic nerve head deformation due to intracranial pressure

AJ Feola, JG Myers, J Raykin, L Mulugeta… - … & visual science, 2016 - arvojournals.org
Purpose: Visual impairment and intracranial pressure (VIIP) syndrome is a health concern
for long-duration spaceflight, and a proposed risk factor is elevation of intracranial pressure …

In vivo 3-dimensional strain map** of the optic nerve head following intraocular pressure lowering by trabeculectomy

MJA Girard, MR Beotra, KS Chin, A Sandhu, M Clemo… - Ophthalmology, 2016 - Elsevier
Purpose To map the 3-dimensional (3D) strain of the optic nerve head (ONH) in vivo after
intraocular pressure (IOP) lowering by trabeculectomy (TE) and to establish associations …

[HTML][HTML] Predictions of optic nerve traction forces and peripapillary tissue stresses following horizontal eye movements

X Wang, LK Fisher, D Milea, JB Jonas… - … & visual science, 2017 - jov.arvojournals.org
Purpose: To use finite element (FE) analysis to predict the optic nerve sheath traction forces
that act on the optic nerve head (ONH) following horizontal eye movements, and the …