In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …

Nuclear hyperpolarization has emerged as a method to dramatically enhance the sensitivity
of NMR spectroscopy. By application of this powerful tool, small molecules with stable …

The conversion of [IrCl (COD)(IMes)](COD= cis, cis-1, 5-cyclooctadiene, IMes= 1, 3-bis (2, 4,
6-trimethyl-phenyl) imidazole-2-ylidene) in the presence of an excess of para-hydrogen (p …

SABRE is emerging as a fast, simple and low-cost hyperpolarization method because of its
ability to regenerate enhanced NMR signals. Generally, SABRE hyperpolarization has been …

Nuclear spin hyperpolarization through signal amplification by reversible exchange
(SABRE), the non-hydrogenative version of para-hydrogen induced polarization, is …

Parahydrogen-induced polarisation (PHIP) is a nuclear spin hyperpolarisation technique
employed to enhance NMR signals for a wide range of molecules. This is achieved by …

15N spin–lattice relaxation dynamics in metronidazole-15N3 and metronidazole-15N2
isotopologues are studied for rational design of 15N-enriched biomolecules for signal …

Here we report on chelating ligands for Signal Amplification By Reversible Exchange
(SABRE) catalysts that permit hyperpolarisation on otherwise sterically hindered substrates …

In this work, the limited sensitivity of magnetic resonance is addressed by using the
hyperpolarisation method relayed signal amplification by reversible exchange (SABRE …

Monosaccharides, such as glucose and fructose, are important to life. In this work we
highlight how the rapid delivery of improved 13C detectability for sugars by nuclear …