Plasmodium spp. parasites that cause malaria disease remain a significant global-health
burden. With the spread of parasites resistant to artemisinin combination therapies in …

During primary infection, the number of HIV-1 particles in plasma increases rapidly, reaches
a peak, and then declines until it reaches a set point level. Understanding the kinetics of …

A within-host viral infection model with both virus-to-cell and cell-to-cell transmissions and
three distributed delays is investigated, in which the first distributed delay describes the …

Malaria infection continues to be a major health problem worldwide and drug resistance in
the major human parasite species, Plasmodium falciparum, is increasing in South East Asia …

Treating HIV-infected patients with a combination of several antiretroviral drugs usually
contributes to a substantial decline in viral load and an increase in CD4+ T cells. However …

The dynamics of a general in-host model with intracellular delay is studied. The model can
describe in vivo infections of HIV-I, HCV, and HBV. It can also be considered as a model for …

Various classes of antiretroviral drugs are used to treat HIV infection, and they target
different stages of the viral life cycle. Age-structured models can be employed to study the …

Virus can disseminate between uninfected target cells via two modes, namely, the diffusion-
limited cell-free viral spread and the direct cell-to-cell transfer using virological synapses. To …

Mathematical models of viral infection have been developed, fitted to data, and provide
insight into disease pathogenesis for multiple agents that cause chronic infection, including …

The dynamics of the late stages of the HIV-1 life cycle are poorly documented. Viral
replication dynamics are typically measured in populations of infected cells, but asynchrony …