Pathophysiology of bronchiectasis

HR Keir, JD Chalmers - Seminars in respiratory and critical care …, 2021 - thieme-connect.com
Bronchiectasis is a complex, heterogeneous disorder defined by both a radiological
abnormality of permanent bronchial dilatation and a clinical syndrome. There are multiple …

Anti–Interleukin-5 therapy is associated with attenuated lung function decline in severe eosinophilic asthma patients from the Belgian Severe Asthma Registry

S Graff, G Brusselle, S Hanon, C Sohy, L Dupont… - The Journal of Allergy …, 2022 - Elsevier
Background Asthmatics have accelerated lung function decline over time compared with
healthy individuals. Objective To evaluate risk factors for accelerated lung function decline …

Severe asthma and long-term Benralizumab effectiveness in real-life

B Sposato, M Scalese, G Camiciottoli… - European Review for …, 2022 - usiena-air.unisi.it
OBJECTIVE: Long-term efficacy of Benralizumab in real life is not clearly known. We
assessed the long-term effectiveness persistence to anti-IL-5R treatment in a group of …

Effect of tezepelumab on lung function in patients with severe, uncontrolled asthma in the phase 3 NAVIGATOR study

A Menzies-Gow, CS Ambrose, G Colice, G Hunter… - Advances in …, 2023 - Springer
Introduction Severe asthma is associated with airway inflammation and airway obstruction.
In the phase 3 NAVIGATOR study, tezepelumab treatment significantly improved pre …

Sex differences in sociodemographic, clinical, and laboratory variables in childhood asthma: A birth cohort study

SE Chiarella, DP Garcia-Guaqueta, LY Drake… - Annals of Allergy …, 2024 - Elsevier
Background There are marked sex differences in the prevalence and severity of asthma,
both during childhood and adulthood. There is a relative lack of comprehensive studies …

[HTML][HTML] Characteristics of patients with severe asthma who experienced treatment failure with omalizumab

T Akaba, M Kondo, F Kobayashi, N Honda… - Pulmonary …, 2021 - Elsevier
Abstract Background Omalizumab, an anti-IgE antibody, has been widely used in many
countries, including Japan. However, some patients do not respond to omalizumab, and the …

Stellenwert der Bronchodilatator-Response bzw. Reversibilitätstestung bei der Diagnose und Therapie des Asthma bronchiale

D Nachtigall, CP Criée - Atemwegs-und Lungenkrankheiten, 2023 - search.proquest.com
Abstract Der Bronchodilatatortest bzw. Reversibilitätstest gilt als zentrale Untersuchung für
die Diagnose eines Asthma bronchiale. Dass das Ansprechen auf die Gabe eines …

[PDF][PDF] Neutrophil Extracellular Traps in Chronic Lung Disease

HR Keir - 2021 - discovery.dundee.ac.uk
There is much overlap in the pathophysiology of bronchiectasis and COPD, and this is
reflected in the recognised association of these two diseases, where studies suggest that up …