GPX4 in cell death, autophagy, and disease
ABSTRACT Selenoprotein GPX4 (glutathione peroxidase 4), originally known as PHGPX
(phospholipid hydroperoxide glutathione peroxidase), is the main oxidoreductase in the use …
(phospholipid hydroperoxide glutathione peroxidase), is the main oxidoreductase in the use …
Metabolism pathways of arachidonic acids: mechanisms and potential therapeutic targets
The arachidonic acid (AA) pathway plays a key role in cardiovascular biology,
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …
carcinogenesis, and many inflammatory diseases, such as asthma, arthritis, etc. Esterified …
[HTML][HTML] The emerging role of ferroptosis in inflammation
Y Sun, P Chen, B Zhai, M Zhang, Y **ang… - Biomedicine & …, 2020 - Elsevier
Ferroptosis is a newly discovered type of cell death triggered by intracellular phospholipid
peroxidation that is morphologically, biologically and genetically distinct from other types of …
peroxidation that is morphologically, biologically and genetically distinct from other types of …
The kidney-related effects of polystyrene microplastics on human kidney proximal tubular epithelial cells HK-2 and male C57BL/6 mice
Background: Understanding the epidemic of chronic kidney disease of uncertain etiology
may be critical for health policies and public health responses. Recent studies have shown …
may be critical for health policies and public health responses. Recent studies have shown …
Effects of arachidonic acid metabolites on cardiovascular health and disease
Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell
membranes and metabolized by cyclooxygenase (COX), cytochrome P450 (CYP) enzymes …
membranes and metabolized by cyclooxygenase (COX), cytochrome P450 (CYP) enzymes …
The road from AKI to CKD: molecular mechanisms and therapeutic targets of ferroptosis
R Guo, J Duan, S Pan, F Cheng, Y Qiao, Q Feng… - Cell death & …, 2023 - nature.com
Acute kidney injury (AKI) is a prevalent pathological condition that is characterized by a
precipitous decline in renal function. In recent years, a growing body of studies have …
precipitous decline in renal function. In recent years, a growing body of studies have …
[HTML][HTML] Therapeutic potential of ginger against COVID-19: Is there enough evidence?
A Jafarzadeh, S Jafarzadeh, M Nemati - Journal of Traditional Chinese …, 2021 - Elsevier
In addition to the respiratory system, severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …
(SARS-CoV-2) strikes other systems, including the digestive, circulatory, urogenital, and …
Iron, ferroptosis, and ischemic stroke
Over 30 million people suffer from the consequences of ischemic stroke. The precise
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …
molecular mechanism of neuronal damage during ischemic stroke remains unclear; …
Perturbed gut microbiome and fecal and serum metabolomes are associated with chronic kidney disease severity
H Wang, A Ainiwaer, Y Song, L Qin, A Peng, H Bao… - Microbiome, 2023 - Springer
Background Chronic kidney disease (CKD) is a severe public health problem associated
with a disordered gut microbiome. However, the functional alterations of microbiota and their …
with a disordered gut microbiome. However, the functional alterations of microbiota and their …
Recent advances of traditional Chinese medicine on the prevention and treatment of COVID-19
DAI Yu-Jie, W Shi-Yao, G Shuai-Shuai… - Chinese Journal of …, 2020 - Elsevier
Coronavirus disease-2019 (COVID-19) is a new highly infectious disease caused by a novel
coronavirus. Recently, the number of new cases infected pneumonia in the world continues …
coronavirus. Recently, the number of new cases infected pneumonia in the world continues …