Following skin wounding, the healing outcome can be: regeneration, repair with normal scar
tissue, repair with hypertrophic scar tissue or the formation of keloids. The role of chemical …

Soft biological tissues are complex materials with a large structural variety, with differences
in behavior, but with some common characteristics. Skin is an archetypal soft tissue which …

Emerging micro-scale medical devices are showing promise, whether in delivering drugs or
extracting diagnostic biomarkers from skin. In progressing these devices through animal …

Hydrogel microneedle patch enables the extraction of skin interstitial fluid (ISF) through in
situ swelling in a minimally invasive manner without assistance of mechano‐chemical …

Touch perception begins with activation of low-threshold mechanoreceptors (LTMRs) in the
periphery. LTMR terminals exhibit tremendous morphological heterogeneity that specifies …

Organisms as diverse as microbes, roundworms, insects, and mammals detect and respond
to applied force. In animals, this ability depends on ionotropic force receptors, known as …

Soft tissue reconstruction has remained a major clinical challenge in dentistry and
regenerative medicine. Although current methods have shown partial success, there are …

Andrographolide (AG) is one of the compounds in Andrographis paniculata, which has a
high antibacterial activity. This paper reports the freeze–thaw method's use to synthesize …

Dermal white adipose tissue (dWAT) is increasingly appreciated as a special fat depot. The
adipocytes in this depot exert a variety of unique effects on their surrounding cells and can …

From a mechanical point of view, human skin appears as a layered composite containing
the stiff thin cover layer presented by the stratum corneum, below which are the more …