The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …

Highlights•The architecture of the cerebral vasculature sculpts the hemodynamics
response.•The BOLD signal is correlated with increases in gamma-band power in the LFP …

Noradrenaline (NA) release from the locus coeruleus (LC) changes activity and connectivity
in neuronal networks across the brain, modulating multiple behavioral states. NA release is …

Molecular motors are diverse enzymes that transduce chemical energy into mechanical
work and, in doing so, perform critical cellular functions such as DNA replication and …

The role of parvalbumin (PV) interneurons in vascular control is poorly understood. Here, we
investigated the hemodynamic responses elicited by optogenetic stimulation of PV …

Accurate identification of brain function is necessary to understand the neurobiology of
cognitive ageing, and thereby promote well-being across the lifespan. A common tool used …

Cortical neural activity is coupled to local arterial diameter and blood flow. However, which
neurons control the dynamics of cerebral arteries is not well understood. We dissected the …

The BOLD fMRI response in the cortex is often assumed to reflect changes in excitatory
neural activity. However, the contribution of inhibitory neurons to BOLD fMRI is unclear …

Functional neuroimaging techniques are widely applied to investigations of human cognition
and disease. The most commonly used among these is blood oxygen level-dependent …

Abstracts Functional connectivity, which reflects the spatial and temporal organization of
intrinsic activity throughout the brain, is one of the most studied measures in human …