[HTML][HTML] The definition of tuberculosis infection based on the spectrum of tuberculosis disease

GB Migliori, CWM Ong, L Petrone, L D'Ambrosio… - Breathe, 2021 - Eur Respiratory Soc
Latent tuberculosis infection was the term traditionally used to indicate tuberculosis (TB)
infection. This term was used to define “a state of persistent immune response to stimulation …

[HTML][HTML] Diagnosis and biomarkers for ocular tuberculosis: From the present into the future

Z Ludi, AA Sule, RP Samy, I Putera, B Schrijver… - Theranostics, 2023 - ncbi.nlm.nih.gov
Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis (Mtb) and can
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …

Biomarker discovery for tuberculosis using metabolomics

Y Yu, XX Jiang, JC Li - Frontiers in molecular biosciences, 2023 - frontiersin.org
Tuberculosis (TB) is the leading cause of death among infectious diseases, and the ratio of
cases in which its pathogen Mycobacterium tuberculosis (Mtb) is drug resistant has been …

Comprehensive lipid and lipid-related gene investigations of host immune responses to characterize metabolism-centric biomarkers for pulmonary tuberculosis

NP Long, NK Anh, NTH Yen, NK Phat, S Park… - Scientific Reports, 2022 - nature.com
Despite remarkable success in the prevention and treatment of tuberculosis (TB), it remains
one of the most devastating infectious diseases worldwide. Management of TB requires an …

[HTML][HTML] Indole: A promising scaffold for the discovery and development of potential anti-tubercular agents

NG Bajad, SK Singh, SK Singh, TD Singh… - Current Research in …, 2022 - Elsevier
Indole-containing small molecules have been reported to have diverse pharmacological
activities. The aromatic heterocyclic scaffold, which resembles various protein structures …

Advances in diagnostic tools for respiratory tract infections: from tuberculosis to COVID-19–changing paradigms?

Z Stojanovic, F Gonçalves-Carvalho… - ERJ Open …, 2022 - Eur Respiratory Soc
Respiratory tract infections (RTIs) are one of the most common reasons for seeking
healthcare, but are amongst the most challenging diseases in terms of clinical decision …

[HTML][HTML] Pharmacometrics in tuberculosis: progress and opportunities

JJ Wilkins, EM Svensson, JP Ernest, RM Savic… - International Journal of …, 2022 - Elsevier
Tuberculosis (TB) remains one of the leading causes of death by a communicable agent,
infecting up to one-quarter of the world's population, predominantly in disadvantaged …

Whole-genome sequencing for resistance prediction and transmission analysis of Mycobacterium tuberculosis complex strains from Namibia

M Claassens, V Dreyer, E Nepolo… - Microbiology …, 2022 - Am Soc Microbiol
Namibia is among 30 countries with a high burden of tuberculosis (TB), with an estimated
incidence of 460 per 100,000 population and around 800 new multidrug-resistant (MDR) TB …

Combination of gallium citrate and levofloxacin induces a distinct metabolome profile and enhances growth inhibition of multidrug-resistant Mycobacterium …

O Ilchenko, E Nikolaevskaya, O Zinchenko… - Frontiers in …, 2024 - frontiersin.org
Introduction Tuberculosis (TB) treatment typically involves a tailored combination of four
antibiotics based on the drug resistance profile of the infecting strain. The increasing drug …

Innovative aspects and applications of single cell technology for different diseases

A Ali, S Manzoor, T Ali, M Asim… - American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Recent developments in single-cell technologies have provided valuable insights from
cancer genomics to complex microbial communities. Single-cell technologies including the …