Functional analysis of a novel de novo variant in PPP5C associated with microcephaly, seizures, and developmental delay

SM Fielder, JA Rosenfeld, LC Burrage, L Emrick… - Molecular genetics and …, 2022 - Elsevier
We describe a proband evaluated through the Undiagnosed Diseases Network (UDN) who
presented with microcephaly, developmental delay, and refractory epilepsy with a de novo …

The human and C. elegans Hsp90 chaperone machinery in the context of steroid receptor clients

A Kaziales - 2021 - mediatum.ub.tum.de
The function of steroid receptors in the cell depends on the chaperone machinery of Hsp90,
as Hsp90 primes steroid receptors for hormone binding and transcriptional activation …

Conservation of the separase regulatory domain

M Melesse, JN Bembenek, IB Zhulin - Biology Direct, 2018 - Springer
We report a protein sequence analysis of the cell cycle regulatory protease, separase. The
sequence and structural conservation of the C-terminal protease domain has long been …

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M Haller, Y Yin, G Haller, T Li, Q Li - development, 2024 - digitalcommons.wustl.edu
Results Generation of An In Vivo Model Utilizing SpDam Technology to Map the Genital AR
Network. Ideally, the murine model would be both amenable to tissue-specific and …

Conservation of separase N-terminal domain

M Melesse, JN Bembenek, IB Zhulin - bioRxiv, 2017 - biorxiv.org
We report a reanalysis of the sequence conservation of the cell cycle regulatory protease,
separase. The sequence and structural conservation of the protease domain has long been …

[CITATION][C] The human and C. elegans Hsp90 chaperone machinery in the context of steroid receptor clients

K Anna