Cognitive neuroscience seeks generalizable theories explaining the relationship between
behavioral, physiological and mental states. In pursuit of such theories, we propose a …

Simultaneous recordings from hundreds or thousands of neurons are becoming routine
because of innovations in instrumentation, molecular tools, and data processing software …

Neurophysiology has long progressed through exploratory experiments and chance
discoveries. Anecdotes abound of researchers listening to spikes in real time and noticing …

Visual stimuli that deviate from the current context elicit augmented responses in the primary
visual cortex (V1). These heightened responses, known as" deviance detection," require …

Contemporary pose estimation methods enable precise measurements of behavior via
supervised deep learning with hand-labeled video frames. Although effective in many cases …

Sound elicits rapid movements of muscles in the face, ears, and eyes that protect the body
from injury and trigger brain-wide internal state changes. Here, we performed quantitative …

Organisms process sensory information in the context of their own moving bodies, an idea
referred to as embodiment. This idea is important for developmental neuroscience, robotics …

Summary Layer 1 (L1) of the neocortex acts as a nexus for the collection and processing of
widespread information. By integrating ascending inputs with extensive top-down activity …

What are the spatial and temporal scales of brainwide neuronal activity? We used swept,
confocally-aligned planar excitation (SCAPE) microscopy to image all cells in a large …

Neuronal responses to similar stimuli change dynamically over time, raising the question of
how internal representations can provide a stable substrate for neural coding. Recent work …