Defining memory CD8 T cell

MD Martin, VP Badovinac - Frontiers in immunology, 2018 - frontiersin.org
CD8 T cells comprising the memory pool display considerable heterogeneity, with individual
cells differing in phenotype and function. This review will focus on our current understanding …

Develo** therapeutic approaches for twenty-first-century emerging infectious viral diseases

RM Meganck, RS Baric - Nature medicine, 2021 - nature.com
The twenty-first century has already recorded more than ten major epidemic or pandemic
virus emergence events, including the ongoing and devastating coronavirus disease 2019 …

TASSEL: software for association map** of complex traits in diverse samples

PJ Bradbury, Z Zhang, DE Kroon, TM Casstevens… - …, 2007 - academic.oup.com
Association analyses that exploit the natural diversity of a genome to map at very high
resolutions are becoming increasingly important. In most studies, however, researchers …

[BOOK][B] Behavioral genetics

R Plomin - 2008 - books.google.com
Behavioral Genetics, Fifth Edition provides an engaging and clear overview of human and
animal behavioral genetics that is designed to introduce students in the behavioral …

Mouse genomic variation and its effect on phenotypes and gene regulation

TM Keane, L Goodstadt, P Danecek, MA White… - Nature, 2011 - nature.com
We report genome sequences of 17 inbred strains of laboratory mice and identify almost ten
times more variants than previously known. We use these genomes to explore the …

Animal models of acute lung injury

G Matute-Bello, CW Frevert… - American Journal of …, 2008 - journals.physiology.org
Acute lung injury in humans is characterized histopathologically by neutrophilic alveolitis,
injury of the alveolar epithelium and endothelium, hyaline membrane formation, and …

Individuality in gut microbiota composition is a complex polygenic trait shaped by multiple environmental and host genetic factors

AK Benson, SA Kelly, R Legge, F Ma… - Proceedings of the …, 2010 - National Acad Sciences
In vertebrates, including humans, individuals harbor gut microbial communities whose
species composition and relative proportions of dominant microbial groups are …

Preclinical mouse cancer models: a maze of opportunities and challenges

CP Day, G Merlino, T Van Dyke - Cell, 2015 - cell.com
Significant advances have been made in develo** novel therapeutics for cancer
treatment, and targeted therapies have revolutionized the treatment of some cancers …

Status and prospects of association map** in plants

C Zhu, M Gore, ES Buckler, J Yu - The plant genome, 2008 - Wiley Online Library
There is tremendous interest in using association map** to identify genes responsible for
quantitative variation of complex traits with agricultural and evolutionary importance. Recent …

The genetics of quantitative traits: challenges and prospects

TFC Mackay, EA Stone, JF Ayroles - Nature Reviews Genetics, 2009 - nature.com
A major challenge in current biology is to understand the genetic basis of variation for
quantitative traits. We review the principles of quantitative trait locus map** and …