The coexistence of immune-mediated inflammatory diseases with depression has long been
recognised. Data that illustrate the intimate associations between peripheral and brain …

Over 60% of rheumatoid arthritis (RA) patients achieve a good response after 12 months of
treatment when following the European league against rheumatism (EULAR) guidelines for …

Background: Rheumatoid arthritis (RA) is a key health issue worldwide. Due to early
identification and effective treatment strategies, the disease pattern of RA has also changed …

Introduction: Most arthritides are associated with pain and psychological distress (clinically
significant depression and anxiety). Pain and depression are mutually exacerbating; both …

RA is a chronic, systemic, autoimmune disease characterized by inflammation and
degradation of the joints, causing significant negative impact on quality of life. In addition to …

Abstract Purpose of Review The purpose of this study was to review the current information
on fatigue in rheumatoid arthritis (RA). Recent Findings Severe fatigue is common among …

Pain is a major and common symptom reported as a top priority in patients with rheumatoid
arthritis (RA). Intuitively, RA-related pain is often considered to be a natural consequence of …

Abstract Interleukin (IL)-6 is produced locally in response to an inflammatory stimulus, and is
able to induce systemic manifestations at distance from the site of inflammation. Its unique …

Background: Recovery of patients with rheumatoid arthritis (RA) depends on several
physical and psychological factors, besides pharmacological treatment. Co-morbid …

Mental well-being relates to multitudinous lifestyle behaviours and morbidities and
underpins healthy aging. Thus far, causal evidence on whether and in what pattern mental …