Background Rutin as a natural flavonoid compound has revealed an extensive range of
therapeutic potentials. Purpose The current paper is focused on the numerous studies on …

The bioavailability of drugs is dependent on several factors such as solubility and the
administration route. A drug with poor aqueous solubility, therefore, poses challenges with …

Hyperpigmentation of the skin refers to a dermatological condition which alters the color of
the skin, making it discolored or darkened. The treatments for hyperpigmentation disorders …

Hyperpigmentation is a common and distressing dermatologic condition. Since tyrosinase
(TYR) plays an essential role in melanogenesis, its inhibition is considered a logical …

Cosmetic dermatology preparations such as bleaching agents are ingredients with skin‐
related biological activities for increasing and improving skin beauty. The possibility of …

Kojic acid has gained its importance after it was known worldwide that the substance
functions primarily as skin-lightening agent. Kojic acid plays a vital role in skin care products …

Today, due to the prevalence of various diseases such as the novel coronavirus (SARS‐
CoV‐2), diabetes, central nervous system diseases, cancer, cardiovascular disorders, and …

The present work designed to improve the skin delivery of arbutin niosome (arbusome) was
prepared via an ultrasonic technique. The arbusome formulations were optimized by …

The abundant synthesis and accretion of melanin inside skin can be caused by activation of
melanogenic enzymes or increase in number of melanocytes. Melasma is defined as …

In the current study, an ultrasonic approach (as green method) was utilized to prepared kojic
acid niosome (kojisome) which aimed to increase the dermal delivery and improving anti …