From conventional to precision therapy in canine mammary cancer: a comprehensive review

G Valdivia, Á Alonso-Diez, D Pérez-Alenza… - Frontiers in veterinary …, 2021 - frontiersin.org
Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …

Naturally-occurring canine mammary tumors as a translational model for human breast cancer

M Gray, J Meehan, C Martínez-Pérez, C Kay… - Frontiers in …, 2020 - frontiersin.org
Despite extensive research over many decades, human breast cancer remains a major
worldwide health concern. Advances in pre-clinical and clinical research has led to …

Spontaneous and induced animal models for cancer research

A Onaciu, R Munteanu, VC Munteanu, D Gulei… - Diagnostics, 2020 - mdpi.com
Considering the complexity of the current framework in oncology, the relevance of animal
models in biomedical research is critical in light of the capacity to produce valuable data with …

A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer

M Inglebert, M Dettwiler, K Hahn, A Letko… - Scientific Reports, 2022 - nature.com
Mammary tumors in dogs hold great potential as naturally occurring breast cancer models in
translational oncology, as they share the same environmental risk factors, key histological …

Mammary glands of women, female dogs and female rats: similarities and differences to be considered in breast cancer research

T Ferreira, A Gama, F Seixas, AI Faustino-Rocha… - Veterinary …, 2023 - mdpi.com
Simple Summary Breast cancer research is frequently performed using a variety of models,
including animal models, in an attempt to provide information that can be translated into …

Canine mammary cancer: State of the art and future perspectives

E Vazquez, Y Lipovka, A Cervantes-Arias… - Animals, 2023 - mdpi.com
Simple Summary Mammary tumors are the most frequent neoplasia in female dogs. They
develop spontaneous cancer and share several biological, clinical, pathological and …

Associations between dog breed and clinical features of mammary epithelial neoplasia in bitches: an epidemiological study of submissions to a single diagnostic …

G Edmunds, S Beck, KU Kale, I Spasic… - Journal of Mammary …, 2023 - Springer
Mammary cancer is one of the most common neoplasms of dogs, primarily bitches. While
studies have been carried out identifying differing risk of mammary neoplasia in different dog …

Profiling canine mammary tumors: A potential model for studying human breast cancer

LM Gherman, P Chiroi, A Nuţu, C Bica… - The Veterinary …, 2024 - Elsevier
Despite all clinical progress recorded in the last decades, human breast cancer (HBC)
remains a major challenge worldwide both in terms of its incidence and its management …

Canine mammary tumors: classification, biomarkers, traditional and personalized therapies

N Nosalova, M Huniadi, Ľ Horňáková… - International Journal of …, 2024 - mdpi.com
In recent years, many studies have focused their attention on the dog as a proper animal
model for human cancer. In dogs, mammary tumors develop spontaneously, involving a …

Doxorubicin treatment modulates chemoresistance and affects the cell cycle in two canine mammary tumour cell lines

M Levi, R Salaroli, F Parenti, R De Maria… - BMC veterinary …, 2021 - Springer
Background Doxorubicin (DOX) is widely used in both human and veterinary oncology
although the onset of multidrug resistance (MDR) in neoplastic cells often leads to …