Its increasing incidence has led stroke to be the second leading cause of death worldwide.
Despite significant advances in recanalization strategies, patients are still at risk for …

One of the most important causes of neurological morbidity and mortality in the world is
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …

The multipotent mesenchymal stem/stromal cells (MSCs), initially discovered from bone
marrow in 1976, have been identified in nearly all tissues of human body now. The …

The tumor microenvironment (TME) is made up of cells and extracellular matrix (non-cellular
component), and cellular components include cancer cells and non-malignant cells such as …

For our immune system to contain or eliminate malignant solid tumours, both myeloid and
lymphoid haematopoietic cells must not only extravasate from the bloodstream into the …

Heparin has been used extensively as an antithrombotic and anticoagulant for close to 100
years. This anticoagulant activity is attributed mainly to the pentasaccharide sequence …

It is well-established that the chemokine CXC motif ligand 13 (CXCL13) and its receptor, the
G-protein coupled receptor (GPCR) CXCR5, play fundamental roles in inflammatory …

G protein–coupled receptors (GPCRs) are a large family comprising> 800 signaling
receptors that regulate numerous cellular and physiologic responses. GPCRs have been …

Stroke is currently one of the most common causes of death and disability in the world, and
its pathophysiology is a complex process, involving the oxidative stress and inflammatory …

Unlike hematological malignancies, solid tumors have proved to be less susceptible to
chimeric antigen receptor (CAR)‐T cell therapy, which is partially caused by reduced …