RNA splicing brings diversity to the eukaryotic proteome. Different spliced variants of a gene
may differ in their structure, function, localization, and stability influencing protein …

Once bound to the epithelium, pathogenic bacteria have to cross epithelial barriers to invade
their human host. In order to achieve this goal, they have to destroy the adherens junctions …

Variation in gut microbiome is associated with wellness and disease in humans, and yet the
molecular mechanisms by which this variation affects the host are not well understood. A …

Bacteria evolved many strategies to survive and persist within host cells. Secretion of
bacterial effectors enables bacteria not only to enter the host cell but also to manipulate host …

Neutrophils have been recognized to play an important role in the pathogenesis of
tuberculosis in recent years. Interferon-induced blood transcriptional signatures in ATB are …

Tuberculosis (TB) continues to remain at the forefront of the infectious disease burden
globally, albeit with some aberrations during the COVID-19 pandemic. Among many factors …

Mycobacterium tuberculosis (Mtb) is one of the major causes of human death. In its battle
with humans, Mtb has fully adapted to its host and developed ways to evade the immune …

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), triggers
enhanced accumulation of lipids to generate foamy macrophages (FMs). This process has …

Tuberculosis disease continues to contribute to the mortality burden globally. Due to the
several shortcomings of the available diagnostic methods, tuberculosis disease continues to …

Although genome-wide association studies have identified single nucleotide polymorphisms
(SNPs) associated with the susceptibility to Mycobacterium avium subsp. paratuberculosis …