[HTML][HTML] Bioactive substances of cyanobacteria and microalgae: Sources, metabolism, and anticancer mechanism insights

A Bouyahya, S Bakrim, I Chamkhi, D Taha… - Biomedicine & …, 2024 - Elsevier
Cyanobacteria and microalgae contain various phytochemicals, including bioactive
components in the form of secondary metabolites, namely flavonoids, phenolic acids …

Betulinic acid for glioblastoma treatment: reality, challenges and perspectives

S Fernandes, M Vieira, C Prudêncio… - International Journal of …, 2024 - mdpi.com
Betulinic acid is a naturally occurring compound that can be obtained through methanolic or
ethanolic extraction from plant sources, as well as through chemical synthesis or microbial …

Cellular and molecular mechanisms underlying the potential of betulinic acid in cancer prevention and treatment

S Banerjee, S Banerjee, A Bishayee, MN Da Silva… - Phytomedicine, 2024 - Elsevier
Background Betulinic acid (BA), which is a pentacyclic triterpenoid found in the bark of
plane, birch, and eucalyptus trees, has emerged as a compound of significant interest in …

Multifunctional roles of betulinic acid in cancer chemoprevention: spotlight on JAK/STAT, VEGF, EGF/EGFR, TRAIL/TRAIL-R, AKT/mTOR and non-coding RNAs in the …

AA Farooqi, A Turgambayeva, G Tashenova… - Molecules, 2022 - mdpi.com
The pursual of novel anticancer molecules from natural sources has gained worthwhile
appreciation, and a significant fraction of conceptual knowledge has revolutionized our …

Unlocking the potential of pyroptosis in tumor immunotherapy: a new horizon in cancer treatment

Q Yin, SY Song, Y Bian, Y Wang, A Deng, J Lv… - Frontiers in …, 2024 - frontiersin.org
Background The interaction between pyroptosis—a form of programmed cell death—and
tumor immunity represents a burgeoning field of interest. Pyroptosis exhibits a dual role in …

Betulinic acid in the treatment of breast cancer: Application and mechanism progress

H Mu, Y Sun, B Yuan, Y Wang - Fitoterapia, 2023 - Elsevier
Betulinic acid (BA) is a pentacyclic triterpene compound, which can be obtained by
separation, chemical synthesis and biotransformation. BA has excellent biological activities …

Recent progress on triterpenoid derivatives and their anticancer potential

ZX Zhao, QY Zou, YH Ma, SL Morris‐Natschke, XY Li… - Phytochemistry, 2024 - Elsevier
Cancer poses a significant global public health challenge, with commonly used adjuvant or
neoadjuvant chemotherapy often leading to adverse side effects and drug resistance …

Terpenoid-mediated targeting of STAT3 signaling in cancer: an overview of preclinical studies

F Khan, P Pandey, M Verma, TK Upadhyay - Biomolecules, 2024 - mdpi.com
Cancer has become one of the most multifaceted and widespread illnesses affecting human
health, causing substantial mortality at an alarming rate. After cardiovascular problems, the …

Phytochemicals for the prevention and treatment of pancreatic cancer: Current progress and future prospects

N Casarcia, P Rogers, E Guld, S Iyer… - British Journal of …, 2023 - Wiley Online Library
Pancreatic cancer is the third leading cause of cancer‐related deaths in the United States,
owing to its aggressive nature and suboptimal treatment options, emphasizing the need for …

Comprehensive overview of different medicinal parts from Morus alba L.: chemical compositions and pharmacological activities

Y Wang, Q Ai, M Gu, H Guan, W Yang… - Frontiers in …, 2024 - frontiersin.org
Morus alba L., a common traditional Chinese medicine (TCM) with a centuries-old medicinal
history, owned various medicinal parts like Mori folium, Mori ramulus, Mori cortex and Mori …