[HTML][HTML] Neural circuitry of salience and reward processing in psychosis
The processing of salient and rewarding stimuli is integral to engaging our attention,
stimulating anticipation for future events, and driving goal-directed behaviors. Widespread …
stimulating anticipation for future events, and driving goal-directed behaviors. Widespread …
Regional cerebral blood flow at rest in schizophrenia and major depressive disorder: a functional neuroimaging meta-analysis
M Boisvert, O Lungu, F Pilon, A Dumais… - Psychiatry Research …, 2023 - Elsevier
Severe mental disorders (SMDs) such as schizophrenia (SCZ), major depressive disorder
(MDD) and bipolar disorder (BD) are associated with altered brain function. Neuroimaging …
(MDD) and bipolar disorder (BD) are associated with altered brain function. Neuroimaging …
Reward anticipation in schizophrenia: A coordinate-based meta-analysis
Reward processing impairments have been linked with positive and negative symptoms of
schizophrenia. Here, we performed a coordinate-based meta-analysis that combined eleven …
schizophrenia. Here, we performed a coordinate-based meta-analysis that combined eleven …
Brexpiprazole in patients with schizophrenia with or without substance use disorder: an observational study
G Lombardozzi, G Trovini, E Amici… - Frontiers in …, 2023 - frontiersin.org
Background Partial dopamine D2 receptor agonists are used for psychotic symptoms in
adults with schizophrenia spectrum disorders. Recently, interest surged for partial dopamine …
adults with schizophrenia spectrum disorders. Recently, interest surged for partial dopamine …
Anhedonia in schizophrenia
Anhedonia has long been considered a cardinal symptom of schizophrenia. This symptom is
strongly associated with poor functional outcome, and limited treatment options are …
strongly associated with poor functional outcome, and limited treatment options are …
The effects of AUT00206, a novel Kv3. 1/3.2 potassium channel modulator, on task-based reward system activation: a test of mechanism in schizophrenia
The pathophysiology of schizophrenia involves abnormal reward processing, thought to be
due to disrupted striatal and dopaminergic function. Consistent with this hypothesis …
due to disrupted striatal and dopaminergic function. Consistent with this hypothesis …
Investigating the association of ventral and dorsal striatal dysfunction during reward anticipation with negative symptoms in patients with schizophrenia and healthy …
M Stepien, A Manoliu, R Kubli, K Schneider… - PLoS …, 2018 - journals.plos.org
Background Negative symptoms are a core feature of schizophrenia and also found in
healthy individuals in subclinical forms. According to the current literature the two negative …
healthy individuals in subclinical forms. According to the current literature the two negative …
Genome‐wide analyses reveal novel opioid use disorder loci and genetic overlap with schizophrenia, bipolar disorder, and major depression
Opioid use disorder (OUD) and mental disorders are often comorbid, with increased
morbidity and mortality. The causes underlying this relationship are poorly understood …
morbidity and mortality. The causes underlying this relationship are poorly understood …
Altered functional connectivity of the nucleus accumbens network between deficit and non-deficit schizophrenia
C Zhou, C Xue, J Chen, N Amdanee, X Tang… - Frontiers in …, 2021 - frontiersin.org
Deficit schizophrenia (DS), which is marked by stable negative symptoms, is regarded as a
homogeneous subgroup of schizophrenia. While DS patients have structurally altered …
homogeneous subgroup of schizophrenia. While DS patients have structurally altered …
Shared and dissociable features of apathy and reward system dysfunction in bipolar I disorder and schizophrenia
BackgroundBipolar disorder I (BD-I) is defined by episodes of mania, depression and
euthymic states. These episodes are among other symptoms characterized by altered …
euthymic states. These episodes are among other symptoms characterized by altered …