Dynamic DNA modifications, such as methylation/demethylation on cytosine, are major
epigenetic mechanisms to modulate gene expression in both eukaryotes and prokaryotes. In …

Ageing is the main risk factor for human neurological disorders. Among the diverse
molecular pathways that govern ageing, epigenetics can guide age-associated decline in …

Roundup and other glyphosate-based herbicides are the most commonly used herbicides in
the world, yet their effects on develo** fish embryos are not clearly understood. The …

In addition to genetic variation, epigenetic mechanisms such as DNA methylation might
make important contributions to heritable phenotypic diversity in populations. However, it is …

Cellular reprogramming resets the epigenetic landscape to drive shifts in transcriptional
programmes and cell identity. The embryonic chick can regenerate a complete neural retina …

The cerebral cortex is composed of a large variety of distinct cell‐types including projection
neurons, interneurons, and glial cells which emerge from distinct neural stem cell lineages …

Hydroxymethylcytosine (5hmC), a distinct epigenetic marker that plays a role in DNA active
demethylation, has been reported to be important for embryonic development and may …

While cerebral underdevelopment is a hallmark of fetal alcohol spectrum disorders (FASD),
the mechanism (s) guiding the broad cortical neurodevelopmental deficits are not clear …

The dental pulp is critical for the production of odontoblasts to create reparative dentin. In
recent years, dental pulp has become a promising source of mesenchymal stem cells that …

Tet enzymes are epigenetic modifiers that impact gene expression via 5mC to 5hmC
oxidation. Previous work demonstrated the requirement for Tet and 5hmC during zebrafish …