Macrophage phenotype and function in different stages of atherosclerosis
The remarkable plasticity and plethora of biological functions performed by macrophages
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …
have enticed scientists to study these cells in relation to atherosclerosis for> 50 years, and …
Guidelines on models of diabetic heart disease
Diabetes is a major risk factor for cardiovascular diseases, including diabetic
cardiomyopathy, atherosclerosis, myocardial infarction, and heart failure. As cardiovascular …
cardiomyopathy, atherosclerosis, myocardial infarction, and heart failure. As cardiovascular …
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1
JE Kanter, F Kramer, S Barnhart… - Proceedings of the …, 2012 - National Acad Sciences
The mechanisms that promote an inflammatory environment and accelerated
atherosclerosis in diabetes are poorly understood. We show that macrophages isolated from …
atherosclerosis in diabetes are poorly understood. We show that macrophages isolated from …
Monocytes, macrophages, and metabolic disease in atherosclerosis
Atherosclerotic cardiovascular disease (CVD) is a lipid-driven chronic inflammatory disease,
in which macrophages are responsible for taking up these lipids and driving disease …
in which macrophages are responsible for taking up these lipids and driving disease …
Commonality in chronic inflammatory diseases: periodontitis, diabetes, and coronary artery disease.
The article identifies the commonality in chronic inflammatory diseases like periodontitis,
diabetes, and coronary artery disease. These kinds of diseases are observed in a significant …
diabetes, and coronary artery disease. These kinds of diseases are observed in a significant …
Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors
Type 2 diabetes (T2DM) is characterized by hyperglycemia, dyslipidemia, and increased
inflammation. Previously, we showed that high glucose (HG) induces Toll-like receptor (TLR) …
inflammation. Previously, we showed that high glucose (HG) induces Toll-like receptor (TLR) …
Stress hyperglycemia, insulin treatment, and innate immune cells
Hyperglycemia (HG) and insulin resistance are the hallmarks of a profoundly altered
metabolism in critical illness resulting from the release of cortisol, catecholamines, and …
metabolism in critical illness resulting from the release of cortisol, catecholamines, and …
[HTML][HTML] Omega-3 fatty acid fish oil dietary supplements contain saturated fats and oxidized lipids that may interfere with their intended biological benefits
RP Mason, SCR Sherratt - Biochemical and biophysical research …, 2017 - Elsevier
Widely available fish oil dietary supplements (DS) may contain fats and oxidized lipids in
addition to the beneficial omega-3 fatty acids (OM3FAs) for which they are purchased. Little …
addition to the beneficial omega-3 fatty acids (OM3FAs) for which they are purchased. Little …
Mechanisms for oxidative stress in diabetic cardiovascular disease
S Pennathur, JW Heinecke - Antioxidants & redox signaling, 2007 - liebertpub.com
Obesity, metabolic syndrome, and diabetes are increasingly prevalent in Western society,
and they markedly increase the risk for atherosclerotic vascular disease, the major cause of …
and they markedly increase the risk for atherosclerotic vascular disease, the major cause of …
Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
P Soni - US Patent 9,610,272, 2017 - Google Patents
In various embodiments, the present invention provides methods of reducing the risk of a
cardiovascular event in a subject on statin therapy and, in particular, a method of reducing …
cardiovascular event in a subject on statin therapy and, in particular, a method of reducing …