Abstract HYpothesis testing using PHYlogenies (HyPhy) is a scriptable, open-source
package for fitting a broad range of evolutionary models to multiple sequence alignments …

Researchers studying the evolution of viral pathogens and other organisms increasingly
encounter and use large and complex data sets from multiple different sources. Statistical …

Phylogenies are central to many research areas in biology and commonly estimated using
likelihood-based methods. Unfortunately, any likelihood-based method, including Bayesian …

Zusammenfassung Das Konzept der Evolution ist in der modernen Biologie von zentraler
Bedeutung. Deswegen liefert die Phylogenetik, die Lehre über die Verwandschaften und …

Optimization problems are becoming increasingly difficult challenges as a result of the
definition of more realistic formulations and the availability of larger input data. Fortunately …

Computing ancestral ranges via the Dispersion Extinction and Cladogensis (DEC) model of
biogeography is characterized by an exponential number of states relative to the number of …

Phylogenetics study the evolutionary history of organisms using an iterative process of
creating and evaluating phylogenetic trees. This process is very computationally intensive; …

Hardware accelerators are used to speed up computationally expensive applications in
many scientific fields. However, offloading tasks to accelerator cards requires data to be …

Phylogenetic inference is the process of reconstructing the evolutionary history of species
based on their traits, nowadays mostly using molecular sequence data. Current state-of-the …

Disaggregated computer architectures eliminate resource fragmentation in next-generation
datacenters by enabling virtual machines to employ resources such as CPUs, memory, and …