Zebrafish as a model organism for neurodegenerative disease

K Chia, A Klingseisen, D Sieger… - Frontiers in molecular …, 2022 - frontiersin.org
The zebrafish is increasingly recognized as a model organism for translational research into
human neuropathology. The zebrafish brain exhibits fundamental resemblance with human …

[HTML][HTML] An overall view of the most common experimental models for multiple sclerosis

S Dedoni, M Scherma, C Camoglio, C Siddi… - Neurobiology of …, 2023 - Elsevier
Multiple sclerosis (MS) is a complex chronic disease with an unknown etiology. It is
considered an inflammatory demyelinating and neurodegenerative disorder of the central …

Modeling neurodegenerative disorders in zebrafish

AA Bashirzade, KN Zabegalov, AD Volgin… - Neuroscience & …, 2022 - Elsevier
Neurodegeneration is a major cause of Alzheimer's, Parkinson's, Huntington's, multiple and
amyotrophic lateral sclerosis, pontocerebellar hypoplasia, dementia and other related brain …

The effects of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) on the cognitive and motor functions in rodents: A systematic review and meta-analysis

A Narmashiri, M Abbaszadeh, A Ghazizadeh - … & Biobehavioral Reviews, 2022 - Elsevier
Memory and motor deficits are commonly identified in Parkinson's disease (PD). 1-Methyl-4-
phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP) is transformed to MPP+ via monoamine oxidase …

Aluminium exposure leads to neurodegeneration and alters the expression of marker genes involved to parkinsonism in zebrafish brain

T Capriello, G Di Meglio, A De Maio, R Scudiero… - Chemosphere, 2022 - Elsevier
Aluminium, despite being extremely widespread in the world, is a non-essential metal to
human metabolism. This metal is known to have toxic effects on a variety of organs including …

A critical review of zebrafish models of Parkinson's disease

JM Doyle, RP Croll - Frontiers in Pharmacology, 2022 - frontiersin.org
A wide variety of human diseases have been modelled in zebrafish, including various types
of cancer, cardiovascular diseases and neurodegenerative diseases like Alzheimer's and …

Towards improved screening of toxins for Parkinson's risk

L Shan, HJ Heusinkveld, KC Paul, S Hughes… - npj Parkinson's …, 2023 - nature.com
Parkinson's disease (PD) is a chronic, progressive and disabling neurodegenerative
disorder. The prevalence of PD has risen considerably over the past decades. A growing …

Zebrafish: A model deciphering the impact of flavonoids on neurodegenerative disorders

K Mhalhel, M Sicari, L Pansera, J Chen, M Levanti… - Cells, 2023 - mdpi.com
Over the past century, advances in biotechnology, biochemistry, and pharmacognosy have
spotlighted flavonoids, polyphenolic secondary metabolites that have the ability to modulate …

Removal of pharmaceutical compounds and toxicology study in wastewater using Malaysian fungal Ganoderma lucidum

ZM Hanafiah, WHMW Mohtar, WAAQI Wan, AS Bithi… - Chemosphere, 2024 - Elsevier
Elevated usage of pharmaceutical products leads to the accumulation of emerging
contaminants in sewage. In the current work, Ganoderma lucidum (GL) was used to remove …

Parkinson's disease model in zebrafish using intraperitoneal MPTP injection

NA Omar, J Kumar, SL Teoh - Frontiers in Neuroscience, 2023 - frontiersin.org
Introduction Parkinson's disease (PD) is the second most common neurodegenerative
disease that severely affects the quality of life of patients and their family members …