Role of fibroblasts in wound healing and tissue remodeling on Earth and in space

F Cialdai, C Risaliti, M Monici - Frontiers in bioengineering and …, 2022 - frontiersin.org
Wound healing (WH) and the role fibroblasts play in the process, as well as healing
impairment and fibroblast dysfunction, have been thoroughly reviewed by other authors. We …

Usefulness of complete blood count (CBC) to assess cardiovascular and metabolic diseases in clinical settings: a comprehensive literature review

IH Seo, YJ Lee - Biomedicines, 2022 - mdpi.com
Complete blood count (CBC) is one of the most common blood tests requested by clinicians
and evaluates the total numbers and characteristics of cell components in the blood …

The future of personalized medicine in space: from observations to countermeasures

E Pavez Loriè, S Baatout, A Choukér… - … in bioengineering and …, 2021 - frontiersin.org
The aim of personalized medicine is to detach from a “one-size fits all approach” and
improve patient health by individualization to achieve the best outcomes in disease …

Neuro-consequences of the spaceflight environment

SD Mhatre, J Iyer, S Puukila, AM Paul… - Neuroscience & …, 2022 - Elsevier
As human space exploration advances to establish a permanent presence beyond the Low
Earth Orbit (LEO) with NASA's Artemis mission, researchers are striving to understand and …

Microgravity and immune cells

H Lv, H Yang, C Jiang, J Shi… - Journal of the …, 2023 - royalsocietypublishing.org
The microgravity environment experienced during spaceflight severely impaired immune
system, making astronauts vulnerable to various diseases that seriously threaten the health …

May the force be with you (or not): The immune system under microgravity

M ElGindi, J Sapudom, IH Ibrahim, M Al-Sayegh… - Cells, 2021 - mdpi.com
All terrestrial organisms have evolved and adapted to thrive under Earth's gravitational force.
Due to the increase of crewed space flights in recent years, it is vital to understand how the …

Next generation of astronauts or ESA astronaut 2.0 concept and spotlight on immunity

P Jacob, C Oertlin, B Baselet, LS Westerberg… - npj …, 2023 - nature.com
Although we have sent humans into space for more than 50 years, crucial questions
regarding immune response in space conditions remain unanswered. There are many …

Similarities between disuse and age‐induced bone loss

EG Buettmann, GM Goldscheitter… - Journal of Bone and …, 2022 - Wiley Online Library
Disuse and aging are known risk factors associated with low bone mass and quality
deterioration, resulting in increased fracture risk. Indeed, current and emerging evidence …

Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight

JS Garcia-Medina, K Sienkiewicz… - Precision Clinical …, 2024 - academic.oup.com
Abstract Background The Inspiration4 (I4) mission, the first all-civilian orbital flight mission,
investigated the physiological effects of short-duration spaceflight through a multi-omic …

The impact of microgravity on immunological states

J Hicks, M Olson, C Mitchell, CM Juran, AM Paul - Immunohorizons, 2023 - journals.aai.org
As we explore other planetary bodies, astronauts will face unique environmental and
physiological challenges. The human immune system has evolved under Earth's …