Post-operative cognitive dysfunction: an exploration of the inflammatory hypothesis and novel therapies

DR Skvarc, M Berk, LK Byrne, OM Dean, S Dodd… - Neuroscience & …, 2018 - Elsevier
Abstract Post-Operative Cognitive Dysfunction (POCD) is a highly prevalent condition with
significant clinical, social and financial impacts for patients and their communities. The …

Ketamine abuse potential and use disorder

Y Liu, D Lin, B Wu, W Zhou - Brain research bulletin, 2016 - Elsevier
Ketamine is a noncompetitive antagonist of N-methyl-d-asparate (NMDA) receptor and has
been long used as an anesthetic agent in humans and veterinary medicine. The present …

Ketamine applications beyond anesthesia–A literature review

A Nowacka, M Borczyk - European journal of pharmacology, 2019 - Elsevier
Ketamine's clinical use began in the 1970s. Physicians benefited from its safety and ability to
induce short-term anesthesia and analgesia. The psychodysleptic effects caused by the …

[HTML][HTML] Pharmacological management of cancer pain: Novel therapeutics

CG Virgen, N Kelkar, A Tran, CM Rosa… - Biomedicine & …, 2022 - Elsevier
Patients diagnosed with cancer often experience pain during their treatment course, making
it difficult to care for themselves and continue with their activities of daily living. When cancer …

Autophagy in traumatic brain injury: a new target for therapeutic intervention

L Zhang, H Wang - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Traumatic brain injury (TBI) is one of the most devastating forms of brain injury. Many
pathological mechanisms such as oxidative stress, apoptosis and inflammation all contribute …

[PDF][PDF] Clinical uses of ketamine in children: a narrative review

A Bali, AK Dang, DA Gonzalez, R Kumar, S Asif - Cureus, 2022 - cureus.com
Ketamine is a phencyclidine derivative that acts as a noncompetitive N-methyl-D-aspartate
as well as a glutamate receptor antagonist. It also has other minor mechanisms that …

Ketamine inhibits colorectal cancer cells malignant potential via blockage of NMDA receptor

W Duan, J Hu, Y Liu - Experimental and molecular pathology, 2019 - Elsevier
Ketamine, a common N-methyl-d-aspartate receptor (NMDAR) antagonist, is an option for
cancer pain treatment in clinical practice. Ketamine has been shown to have the capacity to …

Ketamine drug as an inhibitor for the corrosion of 316 stainless steel in 2M HCl solution

M Abdallah, M Alfakeer, AM Alonazi… - International Journal of …, 2019 - Elsevier
Ketamine drug was examined as an inhibitor of the corrosion of 316 stainless steel in 2MHCl
solution using weight loss, galvanostatic polarization, potentiodynamic anodic polarization …

Efficacy and safety of ketamine to treat Cancer Pain in Adult patients: a systematic review

J Jiao, J Fan, Y Zhang, L Chen - Journal of pain and symptom management, 2024 - Elsevier
Context Ketamine is a well-characterized anesthetic agent, and subanesthetic ketamine
possesses analgesic effects in both acute and chronic pain. Objectives A systematic review …

[HTML][HTML] The efficacy of ketamine for acute and chronic pain in patients with cancer: a systematic review of randomized controlled trials

L Azari, H Hemati, R Tavasolian, S Shahdab… - Healthcare, 2024 - mdpi.com
Managing cancer-related pain poses significant challenges, prompting research into
alternative approaches such as ketamine. This systematic review aims to analyze and …