Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a
variety of fascinating ways. A striking example of this is the remodelling of intracellular …

Members of the Flaviviridae virus family comprise a large group of enveloped viruses with a
single-strand RNA genome of positive polarity. Several genera belong to this family …

Zoonotic coronavirus (CoV) infections, such as those responsible for the current severe
acute respiratory syndrome-CoV 2 (SARS-CoV-2) pandemic, cause grave international …

More than two decades of intense research has provided a detailed understanding of
hepatitis C virus (HCV), which chronically infects 2% of the world's population. This effort has …

Arbidol (ARB) is a Russian-made small indole-derivative molecule, licensed in Russia and
China for prophylaxis and treatment of influenza and other respiratory viral infections. It also …

Positive-strand RNA viruses replicate in close association with rearranged intracellular
membranes. For hepatitis C virus (HCV) and severe acute respiratory syndrome coronavirus …

Positive single-strand RNA (+ RNA) viruses can remodel host cell membranes to induce a
replication organelle (RO) isolating the replication of their genome from innate immunity …

The availability of the first molecular clone of the hepatitis C virus (HCV) genome allowed
the identification and biochemical characterization of two viral enzymes that are targets for …

Cytoplasmic lipid droplets are important organelles in nearly every eukaryotic and some
prokaryotic cells. Storing and providing energy is their main function, but they do not work in …

Hepatitis C virus (HCV) is an important human pathogen that causes hepatitis, liver cirrhosis
and hepatocellular carcinoma. It imposes a serious problem to public health in the world as …