Amyloid oligomers: A joint experimental/computational perspective on Alzheimer's disease, Parkinson's disease, type II diabetes, and amyotrophic lateral sclerosis
Protein misfolding and aggregation is observed in many amyloidogenic diseases affecting
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …
either the central nervous system or a variety of peripheral tissues. Structural and dynamic …
Food protein aggregation and its application
Z Zhu, AP Bassey, Y Cao, Y Ma, M Huang… - Food research …, 2022 - Elsevier
The phenomenon of protein aggregation in food science is very common, but the formation
mechanism is unclear. The formation of protein aggregates (PAs) is influenced by various …
mechanism is unclear. The formation of protein aggregates (PAs) is influenced by various …
Changes in structure, rheological property and antioxidant activity of soy protein isolate fibrils by ultrasound pretreatment and EGCG
X Tong, J Cao, T Tian, B Lyu, L Miao, Z Lian, W Cui… - Food …, 2022 - Elsevier
Impacts of ultrasound pretreatment on the formation of soy protein fibrils, interaction of soy
protein fibrils and EGCG, rheological property and antioxidant activity of the complex, and …
protein fibrils and EGCG, rheological property and antioxidant activity of the complex, and …
Phase separation in biology; functional organization of a higher order
Inside eukaryotic cells, macromolecules are partitioned into membrane-bounded
compartments and, within these, some are further organized into non-membrane-bounded …
compartments and, within these, some are further organized into non-membrane-bounded …
Mass photometric detection and quantification of nanoscale α-synuclein phase separation
Protein liquid–liquid phase separation can lead to disease-related amyloid fibril formation.
The mechanisms of conversion of monomeric protein into condensate droplets and of the …
The mechanisms of conversion of monomeric protein into condensate droplets and of the …
Simulation studies of amyloidogenic polypeptides and their aggregates
Amyloids, fibrillar assembly of (poly) peptide chains, are associated with neurodegenerative
illnesses such as Alzheimer's and Parkinson's diseases, for which there are no cures. The …
illnesses such as Alzheimer's and Parkinson's diseases, for which there are no cures. The …
Food-grade Pickering emulsions stabilized by ovotransferrin fibrils
Z Wei, J Cheng, Q Huang - Food Hydrocolloids, 2019 - Elsevier
The present work aimed to explore the feasibility of fabricating stable food-grade Pickering
emulsions stabilized by ovotransferrin (OVT) fibrils. Raman imaging microscopy and …
emulsions stabilized by ovotransferrin (OVT) fibrils. Raman imaging microscopy and …
Role of water in protein aggregation and amyloid polymorphism
A variety of neurodegenerative diseases are associated with amyloid plaques, which begin
as soluble protein oligomers but develop into amyloid fibrils. Our incomplete understanding …
as soluble protein oligomers but develop into amyloid fibrils. Our incomplete understanding …
High-resolution probing of early events in amyloid-β aggregation related to Alzheimer's disease
In Alzheimer's disease (AD), soluble oligomers of amyloid-β (Aβ) are emerging as a crucial
entity in driving disease progression as compared to insoluble amyloid deposits. The lacuna …
entity in driving disease progression as compared to insoluble amyloid deposits. The lacuna …
[HTML][HTML] Significance of native PLGA nanoparticles in the treatment of Alzheimer's disease pathology
Alzheimer's disease (AD) is believed to be triggered by increased levels/aggregation of β-
amyloid (Aβ) peptides. At present, there is no effective disease-modifying treatment for AD …
amyloid (Aβ) peptides. At present, there is no effective disease-modifying treatment for AD …