Glioma targeted therapy: insight into future of molecular approaches

K Yang, Z Wu, H Zhang, N Zhang, W Wu, Z Wang… - Molecular cancer, 2022 - Springer
Gliomas are the common type of brain tumors originating from glial cells. Epidemiologically,
gliomas occur among all ages, more often seen in adults, which males are more susceptible …

Emerging therapies for glioblastoma: current state and future directions

L Rong, N Li, Z Zhang - Journal of Experimental & Clinical Cancer …, 2022 - Springer
Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an
extremely poor prognosis. Given the poor survival with currently approved treatments for …

Association of autologous tumor lysate-loaded dendritic cell vaccination with extension of survival among patients with newly diagnosed and recurrent glioblastoma: a …

LM Liau, K Ashkan, S Brem, JL Campian… - JAMA …, 2023 - jamanetwork.com
Importance Glioblastoma is the most lethal primary brain cancer. Clinical outcomes for
glioblastoma remain poor, and new treatments are needed. Objective To investigate …

Current advance of nanotechnology in diagnosis and treatment for malignant tumors

B Wang, S Hu, Y Teng, J Chen, H Wang, Y Xu… - … and Targeted Therapy, 2024 - nature.com
Cancer remains a significant risk to human health. Nanomedicine is a new multidisciplinary
field that is garnering a lot of interest and investigation. Nanomedicine shows great potential …

Role of m6A writers, erasers and readers in cancer

Z Fang, W Mei, C Qu, J Lu, L Shang, F Cao… - … hematology & oncology, 2022 - Springer
Abstract The N (6)-methyladenosine (m6A) modification is the most pervasive modification of
human RNAs. In recent years, an increasing number of studies have suggested that m6A …

Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future …

PY Wen, M Weller, EQ Lee, BM Alexander… - Neuro …, 2020 - academic.oup.com
Glioblastomas are the most common form of malignant primary brain tumor and an important
cause of morbidity and mortality. In recent years there have been important advances in …

Carbon dots supported single Fe atom nanozyme for drug-resistant glioblastoma therapy by activating autophagy-lysosome pathway

P Muhammad, S Hanif, J Li, A Guller, FU Rehman… - Nano Today, 2022 - Elsevier
Glioblastoma (GBM) is a fatal and recurrent brain cancer without any complete prevailing
remedy. Here, we explored single-atom nanozyme-mediated catalytic therapy to precisely …

Neurobiological effects of gallic acid: Current perspectives

MS Bhuia, MM Rahaman, T Islam, MH Bappi… - Chinese medicine, 2023 - Springer
Gallic acid (GA) is a phenolic molecule found naturally in a wide range of fruits as well as in
medicinal plants. It has many health benefits due to its antioxidant properties. This study …

Oncolytic viruses engineered to enforce cholesterol efflux restore tumor-associated macrophage phagocytosis and anti-tumor immunity in glioblastoma

S Wang, W Yan, L Kong, S Zuo, J Wu, C Zhu… - Nature …, 2023 - nature.com
The codependency of cholesterol metabolism sustains the malignant progression of
glioblastoma (GBM) and effective therapeutics remain scarce. In orthotopic GBM models in …

[HTML][HTML] Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions

M Hashemi, S Etemad, S Rezaei, S Ziaolhagh… - Biomedicine & …, 2023 - Elsevier
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …