Drug-induced kidney disease occurs primarily in patients with underlying risk factors. A
number of factors enhance the vulnerability of the kidney to the nephrotoxic effects of drugs …

Background Human exposure to mercury leads to a variety of pathologies involving
numerous organ systems including the immune system. A paucity of epidemiological studies …

Background An endemic of chronic kidney disease (CKD) of unknown cause among rural
inhabitants in Central America has been identified. Young and otherwise healthy men …

Acute interstitial nephritis (AIN) is an under recognized and under diagnosed cause of acute
kidney injury (AKI). It is estimated to account for 15–20% of cases of AKI; it is the reported …

Currently in Europe, despite the many advances in production technology of synthetic drugs,
the interest in natural herbal medicines continues to increase. One of the reasons for their …

Anatomically, the kidneys are paired, bean-shaped (in most mammals), excretory organs
that lie in the retroperitoneum. High blood flow to the kidneys, together with high oxygen …

Background The aim of this study was to investigate the effects of royal jelly on cisplatin-
induced nephrotoxicity and oxidative stress in rats. Methods Adult male Wistar albino rats …

It is now widely appreciated that drug metabolites, in addition to the parent drugs
themselves, can mediate the serious adverse effects exhibited by some new therapeutic …

Background. Paraquat (PQ) is a non-selective herbicide that generates reactive oxygen
species in vivo. We hypothesized that acute kidney injury (AKI) in patients with acute PQ …

According to the WHO, about 3 million people die each year due to ambient air pollution.
Most of the in vivo studies on the PM 2.5 effects have been done on respiratory and …