Timing of lifespan influences on brain and cognition
Modifiable risk and protective factors for boosting brain and cognitive development and
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
preventing neurodegeneration and cognitive decline are embraced in neuroimaging …
A perspective on brain-age estimation and its clinical promise
Brain-age estimation has gained increased attention in the neuroscientific community owing
to its potential use as a biomarker of brain health. The difference between estimated and …
to its potential use as a biomarker of brain health. The difference between estimated and …
Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality
Biological aging of human organ systems reflects the interplay of age, chronic disease,
lifestyle and genetic risk. Using longitudinal brain imaging and physiological phenotypes …
lifestyle and genetic risk. Using longitudinal brain imaging and physiological phenotypes …
SARS-CoV-2 is associated with changes in brain structure in UK Biobank
There is strong evidence of brain-related abnormalities in COVID-19,,,,,,,,,,,–. However, it
remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder …
remains unknown whether the impact of SARS-CoV-2 infection can be detected in milder …
Brain imaging before and after COVID-19 in UK Biobank
There is strong evidence for brain-related pathologies in COVID-19, some of which could be
a consequence of viral neurotropism, or of neuroinflammation following viral infection. Most …
a consequence of viral neurotropism, or of neuroinflammation following viral infection. Most …
Mind the gap: Performance metric evaluation in brain‐age prediction
Estimating age based on neuroimaging‐derived data has become a popular approach to
develo** markers for brain integrity and health. While a variety of machine‐learning …
develo** markers for brain integrity and health. While a variety of machine‐learning …
[HTML][HTML] Deep neural networks learn general and clinically relevant representations of the ageing brain
The discrepancy between chronological age and the apparent age of the brain based on
neuroimaging data—the brain age delta—has emerged as a reliable marker of brain health …
neuroimaging data—the brain age delta—has emerged as a reliable marker of brain health …
Brain-age prediction: A systematic comparison of machine learning workflows
The difference between age predicted using anatomical brain scans and chronological age,
ie, the brain-age delta, provides a proxy for atypical aging. Various data representations and …
ie, the brain-age delta, provides a proxy for atypical aging. Various data representations and …
Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium
Schizophrenia (SZ) is associated with an increased risk of life-long cognitive impairments,
age-related chronic disease, and premature mortality. We investigated evidence for …
age-related chronic disease, and premature mortality. We investigated evidence for …
The effects of genetic and modifiable risk factors on brain regions vulnerable to ageing and disease
We have previously identified a network of higher-order brain regions particularly vulnerable
to the ageing process, schizophrenia and Alzheimer's disease. However, it remains …
to the ageing process, schizophrenia and Alzheimer's disease. However, it remains …