Spermatogenesis in humans and its affecting factors
FTL Neto, PV Bach, BB Najari, PS Li… - Seminars in cell & …, 2016 - Elsevier
Spermatogenesis is an extraordinary complex process. The differentiation of spermatogonia
into spermatozoa requires the participation of several cell types, hormones, paracrine …
into spermatozoa requires the participation of several cell types, hormones, paracrine …
Endocrine disruptors acting on estrogen and androgen pathways cause reproductive disorders through multiple mechanisms: a review
Increasing contamination of the environment by toxic compounds such as endocrine
disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both …
disrupting chemicals (EDCs) is one of the major causes of reproductive defects in both …
[HTML][HTML] MicroRNAs and spermatogenesis
N Kotaja - Fertility and sterility, 2014 - Elsevier
In mammals, male gametes are produced inside the testis by spermatogenesis, which has
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
MicroRNA-21 regulates the self-renewal of mouse spermatogonial stem cells
MicroRNAs (miRs) play a key role in the control of gene expression in a wide array of tissue
systems, where their functions include the regulation of self-renewal, cellular differentiation …
systems, where their functions include the regulation of self-renewal, cellular differentiation …
Altered profile of seminal plasma microRNAs in the molecular diagnosis of male infertility
C Wang, C Yang, X Chen, B Yao, C Yang… - Clinical …, 2011 - academic.oup.com
BACKGROUND Although microRNAs (miRNAs) play essential roles in spermatogenesis,
little is known about seminal plasma miRNAs in infertile men. We investigated the profile of …
little is known about seminal plasma miRNAs in infertile men. We investigated the profile of …
MicroRNA-449 and microRNA-34b/c function redundantly in murine testes by targeting E2F transcription factor-retinoblastoma protein (E2F-pRb) pathway
MicroRNAs (miRNAs) mainly function as post-transcriptional regulators and are involved in
a wide range of physiological and pathophysiological processes such as cell proliferation …
a wide range of physiological and pathophysiological processes such as cell proliferation …
The sperm nucleus: chromatin, RNA and the nuclear matrix
Within the sperm nucleus the paternal genome remains functionally inert and protected
following protamination. This is marked by a structural morphogenesis that is heralded by a …
following protamination. This is marked by a structural morphogenesis that is heralded by a …
A multi-faceted approach to understanding male infertility: gene mutations, molecular defects and assisted reproductive techniques (ART)
E Tahmasbpour, D Balasubramanian… - Journal of assisted …, 2014 - Springer
Background The assisted reproductive techniques aimed to assist infertile couples have
their own offspring carry significant risks of passing on molecular defects to next …
their own offspring carry significant risks of passing on molecular defects to next …
Genetic aspects of monomorphic teratozoospermia: a review
M De Braekeleer, MH Nguyen, F Morel… - Journal of assisted …, 2015 - Springer
Teratozoospermia is characterized by the presence of spermatozoa with abnormal
morphology over 85% in sperm. When all the spermatozoa display a unique abnormality …
morphology over 85% in sperm. When all the spermatozoa display a unique abnormality …
A microRNA switch regulates the rise in hypothalamic GnRH production before puberty
A sparse population of a few hundred primarily hypothalamic neurons forms the hub of a
complex neuroglial network that controls reproduction in mammals by secreting the'master …
complex neuroglial network that controls reproduction in mammals by secreting the'master …