Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives

I Yousuf, M Bashir, F Arjmand, S Tabassum - Coordination Chemistry …, 2021 - Elsevier
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …

A tale of two cancers: A current concise overview of breast and prostate cancer

F De Silva, J Alcorn - Cancers, 2022 - mdpi.com
Simple Summary Breast and prostate cancers are serious public health issues that create
considerable burden to both people and healthcare systems worldwide. Cancer is a …

Versatile delivery systems for non-platinum metal-based anticancer therapeutic agents

Y Gou, GJ Huang, J Li, F Yang, H Liang - Coordination chemistry reviews, 2021 - Elsevier
Platinum-based anticancer drugs currently available in the market are associated with
severe side effects. Therefore, extensive research has been performed to design and …

Multifunctional silica-based nanoparticles with controlled release of organotin metallodrug for targeted theranosis of breast cancer

K Ovejero Paredes, D Díaz-García… - Cancers, 2020 - mdpi.com
Three different multifunctional nanosystems based on the tethering onto mesoporous silica
nanoparticles (MSN) of different fragments such as an organotin-based cytotoxic compound …

New organotin (IV) complexes with a bis-acyl-hydrazone ligand: Synthesis, crystal structure and immobilization on magnetic mesoporous silica nanoparticles as a …

T Sedaghat, M Aminian, S Abaee, E Hoveizi… - Journal of Molecular …, 2023 - Elsevier
The new binuclear organotin (IV) complexes,(Me 2 Sn) 2 L (1) and (Ph 2 Sn) 2 L (2), have
been synthesized from reaction of R 2 SnCl 2 (R= Me or Ph) with bis (2-hydroxy-1 …

Preparation and study of the antibacterial applications and oxidative stress induction of copper maleamate-functionalized mesoporous silica nanoparticles

D Díaz-García, PR Ardiles, S Prashar… - Pharmaceutics, 2019 - mdpi.com
Mesoporous silica nanoparticles (MSNs) are an interesting class of nanomaterials with
potential applications in different therapeutic areas and that have been extensively used as …

Mesoporous silica nanoparticles functionalized with a dialkoxide diorganotin (IV) compound: In search of more selective systems against cancer cells

D Díaz-García, L Sommerova, A Martisova… - Microporous and …, 2020 - Elsevier
Mesoporous silica nanoparticles (MSN) have been functionalized with the polyamino ligand
N 1-(3-trimethoxysilylpropyl) diethylenetriamine to give the material MSN-DETATMS (M1) …

Nano-based systems and biomacromolecules as carriers for metallodrugs in anticancer therapy

M Poursharifi, MT Wlodarczyk, AJ Mieszawska - Inorganics, 2018 - mdpi.com
Since the discovery of cisplatin and its potency in anticancer therapy, the development of
metallodrugs has been an active area of research. The large choice of transition metals …

Biological Use of Nanostructured Silica-Based Materials Functionalized with Metallodrugs: The Spanish Perspective

D Díaz-García, S Prashar, S Gómez-Ruiz - International Journal of …, 2023 - mdpi.com
Since the pioneering work of Vallet-Regí's group on the design and synthesis of
mesoporous silica-based materials with therapeutic applications, during the last 15 years …

[HTML][HTML] Study of cancer cell cytotoxicity, internalization and modulation of growth factors induced by transferrin-conjugated formulations of metallodrug-functionalized …

D Díaz-García, E Fischer-Fodor, CI Vlad… - Microporous and …, 2021 - Elsevier
Nano-sized materials have shown to have very high potential in anticancer therapy by an
adequate tuning of their functionalization and physico-chemical properties. This study is …