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Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …
variable oxidation states, diverse range of geometries and coordination numbers …
A tale of two cancers: A current concise overview of breast and prostate cancer
F De Silva, J Alcorn - Cancers, 2022 - mdpi.com
Simple Summary Breast and prostate cancers are serious public health issues that create
considerable burden to both people and healthcare systems worldwide. Cancer is a …
considerable burden to both people and healthcare systems worldwide. Cancer is a …
Versatile delivery systems for non-platinum metal-based anticancer therapeutic agents
Y Gou, GJ Huang, J Li, F Yang, H Liang - Coordination chemistry reviews, 2021 - Elsevier
Platinum-based anticancer drugs currently available in the market are associated with
severe side effects. Therefore, extensive research has been performed to design and …
severe side effects. Therefore, extensive research has been performed to design and …
Multifunctional silica-based nanoparticles with controlled release of organotin metallodrug for targeted theranosis of breast cancer
Three different multifunctional nanosystems based on the tethering onto mesoporous silica
nanoparticles (MSN) of different fragments such as an organotin-based cytotoxic compound …
nanoparticles (MSN) of different fragments such as an organotin-based cytotoxic compound …
New organotin (IV) complexes with a bis-acyl-hydrazone ligand: Synthesis, crystal structure and immobilization on magnetic mesoporous silica nanoparticles as a …
The new binuclear organotin (IV) complexes,(Me 2 Sn) 2 L (1) and (Ph 2 Sn) 2 L (2), have
been synthesized from reaction of R 2 SnCl 2 (R= Me or Ph) with bis (2-hydroxy-1 …
been synthesized from reaction of R 2 SnCl 2 (R= Me or Ph) with bis (2-hydroxy-1 …
Preparation and study of the antibacterial applications and oxidative stress induction of copper maleamate-functionalized mesoporous silica nanoparticles
Mesoporous silica nanoparticles (MSNs) are an interesting class of nanomaterials with
potential applications in different therapeutic areas and that have been extensively used as …
potential applications in different therapeutic areas and that have been extensively used as …
Mesoporous silica nanoparticles functionalized with a dialkoxide diorganotin (IV) compound: In search of more selective systems against cancer cells
D Díaz-García, L Sommerova, A Martisova… - Microporous and …, 2020 - Elsevier
Mesoporous silica nanoparticles (MSN) have been functionalized with the polyamino ligand
N 1-(3-trimethoxysilylpropyl) diethylenetriamine to give the material MSN-DETATMS (M1) …
N 1-(3-trimethoxysilylpropyl) diethylenetriamine to give the material MSN-DETATMS (M1) …
Nano-based systems and biomacromolecules as carriers for metallodrugs in anticancer therapy
Since the discovery of cisplatin and its potency in anticancer therapy, the development of
metallodrugs has been an active area of research. The large choice of transition metals …
metallodrugs has been an active area of research. The large choice of transition metals …
Biological Use of Nanostructured Silica-Based Materials Functionalized with Metallodrugs: The Spanish Perspective
Since the pioneering work of Vallet-Regí's group on the design and synthesis of
mesoporous silica-based materials with therapeutic applications, during the last 15 years …
mesoporous silica-based materials with therapeutic applications, during the last 15 years …
[HTML][HTML] Study of cancer cell cytotoxicity, internalization and modulation of growth factors induced by transferrin-conjugated formulations of metallodrug-functionalized …
Nano-sized materials have shown to have very high potential in anticancer therapy by an
adequate tuning of their functionalization and physico-chemical properties. This study is …
adequate tuning of their functionalization and physico-chemical properties. This study is …