Hallmarks of brain aging: adaptive and pathological modification by metabolic states

MP Mattson, TV Arumugam - Cell metabolism, 2018 - cell.com
During aging, the cellular milieu of the brain exhibits tell-tale signs of compromised
bioenergetics, impaired adaptive neuroplasticity and resilience, aberrant neuronal network …

The prefrontal cortex and obesity: a health neuroscience perspective

CJ Lowe, AC Reichelt, PA Hall - Trends in cognitive sciences, 2019 - cell.com
In the modern obesogenic environment, limiting calorie-dense food consumption is partially
dependent on the capacity of individuals to override visceral reactions to hyperpalatable and …

Socioeconomic status, BMI, and brain development in children

E Dennis, P Manza, ND Volkow - Translational Psychiatry, 2022 - nature.com
Low socioeconomic status (SES) in childhood is associated with deficits in executive
function and changes in cortical morphology. Furthermore, rates of childhood obesity are …

Inhibitory control in obesity and binge eating disorder: A systematic review and meta-analysis of neurocognitive and neuroimaging studies

L Lavagnino, D Arnone, B Cao, JC Soares… - … & Biobehavioral Reviews, 2016 - Elsevier
The ability to exercise appropriate inhibitory control is critical in the regulation of body
weight, but the exact mechanisms are not known. In this systematic review, we identified 37 …

Obesity and addiction: neurobiological overlaps

ND Volkow, GJ Wang, D Tomasi, RD Baler - Obesity reviews, 2013 - Wiley Online Library
Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …

Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry

TW Robbins, CM Gillan, DG Smith, S de Wit… - Trends in cognitive …, 2012 - cell.com
A key criticism of the main diagnostic tool in psychiatry, the Diagnostic and Statistical Manual
of Mental Health Disorders (DSM-IV), is that it lacks a biological footing. In this article, we …

Reward, dopamine and the control of food intake: implications for obesity

ND Volkow, GJ Wang, RD Baler - Trends in cognitive sciences, 2011 - cell.com
The ability to resist the urge to eat requires the proper functioning of neuronal circuits
involved in top-down control to oppose the conditioned responses that predict reward from …

Early life adversity and health‐risk behaviors: proposed psychological and neural mechanisms

KA Duffy, KA McLaughlin… - Annals of the New York …, 2018 - Wiley Online Library
Early life adversity (ELA) is associated with poorer health in adulthood, an association
explained, at least in part, by increased engagement in health‐risk behaviors (HRBs). In this …

Examining the relationship between obesity and cognitive function: a systematic literature review

C Prickett, L Brennan, R Stolwyk - Obesity research & clinical practice, 2015 - Elsevier
The increasing prevalence of both obesity and dementia is a significant public health
concern, especially as recent research demonstrates a significant relationship between …

Reward mechanisms in obesity: new insights and future directions

PJ Kenny - Neuron, 2011 - cell.com
Food is consumed in order to maintain energy balance at homeostatic levels. In addition,
palatable food is also consumed for its hedonic properties independent of energy status …