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Hallmarks of brain aging: adaptive and pathological modification by metabolic states
During aging, the cellular milieu of the brain exhibits tell-tale signs of compromised
bioenergetics, impaired adaptive neuroplasticity and resilience, aberrant neuronal network …
bioenergetics, impaired adaptive neuroplasticity and resilience, aberrant neuronal network …
The prefrontal cortex and obesity: a health neuroscience perspective
In the modern obesogenic environment, limiting calorie-dense food consumption is partially
dependent on the capacity of individuals to override visceral reactions to hyperpalatable and …
dependent on the capacity of individuals to override visceral reactions to hyperpalatable and …
Socioeconomic status, BMI, and brain development in children
E Dennis, P Manza, ND Volkow - Translational Psychiatry, 2022 - nature.com
Low socioeconomic status (SES) in childhood is associated with deficits in executive
function and changes in cortical morphology. Furthermore, rates of childhood obesity are …
function and changes in cortical morphology. Furthermore, rates of childhood obesity are …
Inhibitory control in obesity and binge eating disorder: A systematic review and meta-analysis of neurocognitive and neuroimaging studies
The ability to exercise appropriate inhibitory control is critical in the regulation of body
weight, but the exact mechanisms are not known. In this systematic review, we identified 37 …
weight, but the exact mechanisms are not known. In this systematic review, we identified 37 …
Obesity and addiction: neurobiological overlaps
Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …
disorders in which the saliency of a specific type of reward (food or drug) becomes …
Neurocognitive endophenotypes of impulsivity and compulsivity: towards dimensional psychiatry
A key criticism of the main diagnostic tool in psychiatry, the Diagnostic and Statistical Manual
of Mental Health Disorders (DSM-IV), is that it lacks a biological footing. In this article, we …
of Mental Health Disorders (DSM-IV), is that it lacks a biological footing. In this article, we …
Reward, dopamine and the control of food intake: implications for obesity
The ability to resist the urge to eat requires the proper functioning of neuronal circuits
involved in top-down control to oppose the conditioned responses that predict reward from …
involved in top-down control to oppose the conditioned responses that predict reward from …
Early life adversity and health‐risk behaviors: proposed psychological and neural mechanisms
Early life adversity (ELA) is associated with poorer health in adulthood, an association
explained, at least in part, by increased engagement in health‐risk behaviors (HRBs). In this …
explained, at least in part, by increased engagement in health‐risk behaviors (HRBs). In this …
Examining the relationship between obesity and cognitive function: a systematic literature review
The increasing prevalence of both obesity and dementia is a significant public health
concern, especially as recent research demonstrates a significant relationship between …
concern, especially as recent research demonstrates a significant relationship between …
Reward mechanisms in obesity: new insights and future directions
PJ Kenny - Neuron, 2011 - cell.com
Food is consumed in order to maintain energy balance at homeostatic levels. In addition,
palatable food is also consumed for its hedonic properties independent of energy status …
palatable food is also consumed for its hedonic properties independent of energy status …