The protection afforded by kefir against cyclophosphamide induced testicular toxicity in rats by oxidant antioxidant and histopathological evaluations

S Cetik Yildiz, C Demir, M Cengiz, H Irmak… - Scientific Reports, 2024 - nature.com
Cyclophosphamide (CTX) is the most commonly used effective alkylating drug in cancer
treatment, but its use is restricted because its toxic side effect causes testicular toxicity. CTX …

[HTML][HTML] Protective Effect of Escin Against Kidney Injury: Histopathological and Biochemical Evaluations

M Cengiz, B Peker Cengiz, A Teixeira Andrade… - Current Issues in …, 2024 - mdpi.com
The purpose of the current study was to find out whether escin (ES) safeguarded
experimental rats against cyclophosphamide (CP)-induced kidney injury. Twenty-four rats …

[HTML][HTML] Spray-dried cyclophosphamide-loaded polyhydroxyalkanoate microparticles: design and characterization

S Lipaikin, A Dorokhin, G Ryltseva, A Oberenko… - ADMET and …, 2024 - hrcak.srce.hr
Background and purpose Cyclophosphamide (CP) is a widely used antitumor and
immunosuppressive drug, but it is highly cytotoxic and has carcinogenic and teratogenic …

[HTML][HTML] Immunotherapeutic and Cell-Protective Effects of Probiotic Kefir on Cyclophosphamide‐induced Nephrotoxicity and Urotoxicity in Rats

S Çetik-yıldız, C Demir, M Cengiz, H Irmak… - … Üniversitesi Fen Ve …, 2024 - dergipark.org.tr
To evaluate kefir, a naturally occurring fermented dairy product, with pharmacological and
therapeutic qualities including antioxidant, anti-apoptotic, and anti-inflammatory effects …