Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing
inflammatory diseases of the intestinal tract and generally refers to ulcerative colitis (UC) …

Objective We aimed to provide an evidence-supported update of the ECCO-ESPGHAN
guideline on the medical management of paediatric Crohn's disease [CD]. Methods We …

Background Data are needed to inform the positioning of biologic therapy in the treatment of
moderate-to-severe Crohn's disease, both first line and after previous biologic exposure. We …

Gut inflammation is strongly associated with spondyloarthritis (SpA), as exemplified by the
high prevalence of inflammatory bowel disease (IBD) and the even higher occurrence of …

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal
tract with a multifactorial pathophysiology. Full comprehension of IBD pathology is still out of …

Abstract Background and Aims Following induction/maintenance treatment in the UNITI/IM-
UNITI studies of ustekinumab for Crohn's disease, patients entered a long-term extension for …

Background Vedolizumab, a gut‐selective α4β7 integrin antibody, is approved for
moderately to severely active ulcerative colitis (UC) and Crohn's disease (CD). Aim To report …

Abstract Background and Aims To report results from VISIBLE 2, a randomised, double-
blind, placebo-controlled, phase 3 trial evaluating a new subcutaneous [SC] vedolizumab …

Background Women with inflammatory bowel diseases (IBD) often receive biologicals
during pregnancy to maintain disease remission. Data on outcome of vedolizumab‐exposed …