[HTML][HTML] Macrophages as a therapeutic target to promote diabetic wound healing
It is well established that macrophages are key regulators of wound healing, displaying
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …
impressive plasticity and an evolving phenotype, from an aggressive pro-inflammatory or" …
Lipid-based systemic delivery of siRNA
RNAi technology has brought a new category of treatments for various diseases including
genetic diseases, viral diseases, and cancer. Despite the great versatility of RNAi that can …
genetic diseases, viral diseases, and cancer. Despite the great versatility of RNAi that can …
Inhibitors of indoleamine-2, 3-dioxygenase for cancer therapy: can we see the wood for the trees?
S Löb, A Königsrainer, HG Rammensee… - Nature Reviews …, 2009 - nature.com
Abstract Indoleamine-2, 3-dioxygenase (IDO) is an immunosuppressive enzyme capable of
inhibiting a destructive maternal T cell response against allogeneic fetuses. Expression of …
inhibiting a destructive maternal T cell response against allogeneic fetuses. Expression of …
Employing siRNA tool and its delivery platforms in suppressing cisplatin resistance: approaching to a new era of cancer chemotherapy
Although chemotherapy is a first option in treatment of cancer patients, drug resistance has
led to its failure, requiring strategies to overcome it. Cancer cells are capable of switching …
led to its failure, requiring strategies to overcome it. Cancer cells are capable of switching …
A critical review of novel antibiotic resistance prevention approaches with a focus on postbiotics
Antibiotic resistance is a significant public health issue, causing illnesses that were once
easily treatable with antibiotics to develop into dangerous infections, leading to substantial …
easily treatable with antibiotics to develop into dangerous infections, leading to substantial …
MicroRNAs: control and loss of control in human physiology and disease
Abstract Analysis of the human genome indicates that a large fraction of the genome
sequences are RNAs that do not encode any proteins, also known as non-coding RNAs …
sequences are RNAs that do not encode any proteins, also known as non-coding RNAs …
Antitumor activity and prolonged survival by carbon‐nanotube‐mediated therapeutic siRNA silencing in a human lung xenograft model
Carbon nanotubes are novel nanomaterials that are thought to offer potential benefits to a
variety of biomedical and clinical applications. In this study, the treatment of a human lung …
variety of biomedical and clinical applications. In this study, the treatment of a human lung …
Multifunctional QD-based co-delivery of siRNA and doxorubicin to HeLa cells for reversal of multidrug resistance and real-time tracking
JM Li, YY Wang, MX Zhao, CP Tan, YQ Li, XY Le, LN Ji… - Biomaterials, 2012 - Elsevier
Co-delivery of siRNA and chemotherapeutic agents has been developed to combat
multidrug resistance in cancer therapy. Recently, we developed a series of quantum dots …
multidrug resistance in cancer therapy. Recently, we developed a series of quantum dots …
Efficient siRNA delivery to mammalian cells using layered double hydroxide nanoparticles
Although siRNAs have surpassed expectations in experiments to alter gene expression in
vitro, the lack of an efficient in vivo delivery system still remains a challenge in siRNA …
vitro, the lack of an efficient in vivo delivery system still remains a challenge in siRNA …
Alternative splicing and tumor progression
Alternative splicing is a key molecular mechanism for increasing the functional diversity of
the eukaryotic proteomes. A large body of experimental data implicates aberrant splicing in …
the eukaryotic proteomes. A large body of experimental data implicates aberrant splicing in …