Pulmonary delivery is an alternative route of administration with numerous advantages over
conventional routes of administration. It provides low enzymatic exposure, fewer systemic …

Biological products, including vaccines, blood components, and recombinant therapeutic
proteins, are derived from natural sources such as humans, animals, or microorganisms and …

Inhalation therapy plays an important role in management or treatment of respiratory
diseases such asthma and chronic obstructive pulmonary diseases (COPDs). For decades …

Accurate knowledge of the delivery of locally acting drug products, such as metered-dose
inhaler (MDI) formulations, to large and small airways is essential to develop reliable in …

Asthma and chronic obstructive pulmonary disease (COPD) are major causes of morbidity
and mortality worldwide. Optimal control of these conditions is a constant challenge for both …

The development of generic, single‐entity, drug–device combination products for orally
inhaled drug products is challenging in part because of the complex nature of device design …

The effect of breathing parameters on the airway deposition of the inhaled aerosols with
known size was intensively studied in the literature. However, in the case of dry powder …

Aerosol dosimetry in respiratory airways is relevant for pulmonary drug delivery and
inhalation toxicology. Consequently, computational fluid-particle dynamics (CF-PD) …

Inhaled asbestos fibres have been implicated in causal relationships with increased
frequencies of non-malignant pleural disease, asbestosis, mesothelioma and lung cancer …

Deep lung delivery is crucial for respiratory disease treatment. Although nano and
submicron particles exhibited a good deposition efficiency in deep regions of the lung …