Epigenetics, plasticity, and evolution: How do we link epigenetic change to phenotype?

EJ Duncan, PD Gluckman… - Journal of Experimental …, 2014 - Wiley Online Library
Epigenetic mechanisms are proposed as an important way in which the genome responds
to the environment. Epigenetic marks, including DNA methylation and Histone modifications …

New insights into the role of histone changes in aging

SJ Yi, K Kim - International journal of molecular sciences, 2020 - mdpi.com
Aging is the progressive decline or loss of function at the cellular, tissue, and organismal
levels that ultimately leads to death. A number of external and internal factors, including diet …

Genomics of developmental plasticity in animals

E Lafuente, P Beldade - Frontiers in genetics, 2019 - frontiersin.org
Developmental plasticity refers to the property by which the same genotype produces
distinct phenotypes depending on the environmental conditions under which development …

Hormonal gatekee** via the blood-brain barrier governs caste-specific behavior in ants

L Ju, KM Glastad, L Sheng, J Gospocic, CJ Kingwell… - Cell, 2023 - cell.com
Here, we reveal an unanticipated role of the blood-brain barrier (BBB) in regulating complex
social behavior in ants. Using scRNA-seq, we find localization in the BBB of a key hormone …

Genetic assimilation: a review of its potential proximate causes and evolutionary consequences

IM Ehrenreich, DW Pfennig - Annals of botany, 2016 - academic.oup.com
Background Most, if not all, organisms possess the ability to alter their phenotype in direct
response to changes in their environment, a phenomenon known as phenotypic plasticity …

Epigenetics in insects: genome regulation and the generation of phenotypic diversity

KM Glastad, BG Hunt… - Annual review of …, 2019 - annualreviews.org
Epigenetic inheritance is fundamentally important to cellular differentiation and
developmental plasticity. In this review, we provide an introduction to the field of molecular …

Epigenetic (re)programming of caste-specific behavior in the ant Camponotus floridanus

DF Simola, RJ Graham, CM Brady, BL Enzmann… - Science, 2016 - science.org
INTRODUCTION Eusocial insects, such as ants, live a communal lifestyle within colonies of
close genetic relatives. Colony members are organized into castes defined by behavioral …

Social insect genomes exhibit dramatic evolution in gene composition and regulation while preserving regulatory features linked to sociality

DF Simola, L Wissler, G Donahue… - Genome …, 2013 - genome.cshlp.org
Genomes of eusocial insects code for dramatic examples of phenotypic plasticity and social
organization. We compared the genomes of seven ants, the honeybee, and various solitary …

Cuticular hydrocarbon pheromones for social behavior and their coding in the ant antenna

KR Sharma, BL Enzmann, Y Schmidt, D Moore… - Cell reports, 2015 - cell.com
The sophisticated organization of eusocial insect societies is largely based on the regulation
of complex behaviors by hydrocarbon pheromones present on the cuticle. We used …

Eusocial insects as emerging models for behavioural epigenetics

H Yan, DF Simola, R Bonasio, J Liebig… - Nature Reviews …, 2014 - nature.com
Understanding the molecular basis of how behavioural states are established, maintained
and altered by environmental cues is an area of considerable and growing interest …