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In vitro and in silico modeling of endovascular stroke treatments for acute ischemic stroke
Acute ischemic stroke occurs when a thrombus obstructs a cerebral artery, leading to sub-
optimal blood perfusion to brain tissue. A recently developed, preventive treatment is the …
optimal blood perfusion to brain tissue. A recently developed, preventive treatment is the …
A Review of the Advancements in the in-vitro Modelling of Acute Ischemic Stroke and Its Treatment
In-vitro neurovascular models of large vessel occlusions (LVOs) causing acute ischemic
stroke (AIS) are used extensively for pre-clinical testing of new treatment devices. They …
stroke (AIS) are used extensively for pre-clinical testing of new treatment devices. They …
Blood clot fracture properties are dependent on red blood cell and fibrin content
Thrombus fragmentation during endovascular stroke treatment, such as mechanical
thrombectomy, leads to downstream emboli, resulting in poor clinical outcomes. Clinical …
thrombectomy, leads to downstream emboli, resulting in poor clinical outcomes. Clinical …
Frontline thrombectomy strategy and outcome in acute basilar artery occlusion
Background Novel thrombectomy strategies emanate expeditiously day-by-day counting on
access system, clot retriever device, proximity to and integration with the thrombus, and …
access system, clot retriever device, proximity to and integration with the thrombus, and …
Electroacupuncture pretreatment alleviates rats cerebral ischemia-reperfusion injury by inhibiting ferroptosis
T Ye, N Zhang, A Zhang, X Sun, B Pang, X Wu - Heliyon, 2024 - cell.com
Objective To explore the preventive effect of electroacupuncture pretreatment on stroke in
rats by inhibiting ferroptosis and oxidative stress. Methods Rats were randomly assigned to …
rats by inhibiting ferroptosis and oxidative stress. Methods Rats were randomly assigned to …
Preclinical testing platforms for mechanical thrombectomy in stroke: a review on phantoms, in-vivo animal, and cadaveric models
Preclinical testing platforms have been instrumental in the research and development of
thrombectomy devices. However, there is no single model which fully captures the …
thrombectomy devices. However, there is no single model which fully captures the …
Intracranial artery calcifications profile as a predictor of recanalization failure in endovascular stroke treatment
Background: Acute ischemic stroke with large or medium-vessel occlusion associated with
intracranial artery calcification (IAC) is an infrequent phenomenon presumably associated …
intracranial artery calcification (IAC) is an infrequent phenomenon presumably associated …
Water content for clot composition prediction in acute ischemic stroke
Background Mechanical thrombectomy (MT) has become the gold standard care for treating
acute ischemic stroke (AIS) due to large vessel occlusion. Emerging evidence suggests that …
acute ischemic stroke (AIS) due to large vessel occlusion. Emerging evidence suggests that …
Aspects of ischemic stroke biomechanics derived using ex-vivo and in-vitro methods relating to mechanical thrombectomy
Establishing the underlying biomechanics of acute ischemic stroke (AIS) and its treatment is
fundamental to develo** more effective clinical treatments for one of society's most …
fundamental to develo** more effective clinical treatments for one of society's most …
Preclinical modeling of mechanical thrombectomy
Mechanical thrombectomy to treat large vessel occlusions (LVO) causing a stroke is one of
the most effective treatments in medicine, with a number needed to treat to improve clinical …
the most effective treatments in medicine, with a number needed to treat to improve clinical …