The conventional chemotherapy for leukemia involves frequent dosing, severe side effects
and lack of specificity of such anticancer drugs. The treatment with most of the anti-leukemic …

Drying plays an important role in the preparation of powders, especially in the
pharmaceutical and chemical industries, as it enhances the stability, solubility, and …

Leukaemia cells that are resistant to conventional therapies are thought to reside in
protective niches. Here, we describe light-inducible polymeric retinoic acid (RA)-containing …

Acute promyelocytic leukemia (APL) is phenotypically characterized by the accumulation of
dysplastic promyelocytes, resulting from a cytogenetic condition due to the balanced …

All-trans-retinoic acid (ATRA) exhibits potent cytotoxicities against different cancer cells by
binding to retinoic acid receptors (RARs), which is regarded as the first example of targeted …

Smart polymeric nanocarriers have been developed to deliver therapeutic agents directly to
the intended site of action, with superior efficacy. Herein, a mixture of poly (lactide)(PLA) and …

Background and objective: All-trans retinoic acid (ATRA), a promising therapeutic agent, has
been confirmed in animal experiments as playing a protective role against renal diseases …

In this paper, we describe the synthesis, physicochemical characterization, drug release
kinetics and preliminary biological evaluation of several N-(2-hydroxypropyl) …

Sansalvamide A is a cyclic depsipeptide that is isolated from a marine fungus of the
Fusarium genus. Sansalvamide A exhibits significant antitumor ability. The molecular …

In recent years, microfluidic devices present unique advantages for the development of a
new generation of nanoparticle synthesis method compared to bulk methods. In this study …