Combining physical exercise with cognitive training is a popular intervention in dementia
prevention trials and guidelines. However, it remains unclear what combination strategies …

Background Aging-related cognitive decline and cognitive impairment greatly impacts older
adults' daily life. The worldwide ageing of the population and associated wave of dementia …

The demographic change in industrial countries, with increasingly sedentary lifestyles, has a
negative impact on mental health. Normal and pathological aging leads to cognitive deficits …

It is widely accepted that the brain and the immune system continuously interact during
normal as well as pathological functioning. Human aging is commonly accompanied by low …

Both cognitive intervention and physical exercise benefit cognitive function in older adults. It
has been suggested that combined cognitive and physical intervention may induce larger …

Maintaining a healthy brain is a critical factor for the quality of life of elderly individuals and
the preservation of their independence. Challenging aging brains through cognitive training …

Prior research has found that cognitive benefits of physical exercise and brain health in
older adults may be enhanced when mental exercise is interactive simultaneously, as in …

The unprecedented growth in the number of older adults in our society is accompanied by
the exponential increase in the number of elderly people who will suffer cognitive decline …

Physical as well as cognitive training interventions improve specific cognitive functions but
effects barely generalize on global cognition. Combined physical and cognitive training may …

Human aging is associated with structural and functional brain deteriorations and a
corresponding cognitive decline. Exergaming (ie, physically active video-gaming) has been …