Engineered strategies to enhance tumor penetration of drug-loaded nanoparticles
Nanocarriers have been widely employed in preclinical studies and clinical trials for the
delivery of anticancer drugs. The most important causes of failure in clinical translation of …
delivery of anticancer drugs. The most important causes of failure in clinical translation of …
Unraveling the role of angiogenesis in cancer ecosystems
I Zuazo-Gaztelu, O Casanovas - Frontiers in Oncology, 2018 - frontiersin.org
Activation of the tumor and stromal cell-driven angiogenic program is one of the first
requirements in the tumor ecosystem for growth and dissemination. The understanding of …
requirements in the tumor ecosystem for growth and dissemination. The understanding of …
Magnetic particle targeting for diagnosis and therapy of lung cancers
M Saadat, MKD Manshadi, M Mohammadi… - Journal of Controlled …, 2020 - Elsevier
Over the past decade, the growing interest in targeted lung cancer therapy has guided
researchers toward the cutting edge of controlled drug delivery, particularly magnetic …
researchers toward the cutting edge of controlled drug delivery, particularly magnetic …
Delivery of magnetic micro/nanoparticles and magnetic-based drug/cargo into arterial flow for targeted therapy
MKD Manshadi, M Saadat, M Mohammadi… - Drug …, 2018 - Taylor & Francis
Magnetic drug targeting (MDT) and magnetic-based drug/cargo delivery are emerging
treatment methods which attracting the attention of many researchers for curing different …
treatment methods which attracting the attention of many researchers for curing different …
Microfluidic skin chip with vasculature for recapitulating the immune response of the skin tissue
BS Kwak, SP **, SJ Kim, EJ Kim… - Biotechnology and …, 2020 - Wiley Online Library
There is a considerable need for cell‐based in vitro skin models for studying dermatological
diseases and testing cosmetic products, but current in vitro skin models lack physiological …
diseases and testing cosmetic products, but current in vitro skin models lack physiological …
Mathematical and computational modeling of nano-engineered drug delivery systems
M Shamsi, A Mohammadi, MKD Manshadi… - Journal of Controlled …, 2019 - Elsevier
While the advent of nano-engineered drug delivery systems (DDSs) has revived hopes for
better management of a wide range of pathologies, critical appraisal of the field has shown …
better management of a wide range of pathologies, critical appraisal of the field has shown …
Magnetically assisted intraperitoneal drug delivery for cancer chemotherapy
Intraperitoneal (IP) chemotherapy has revived hopes during the past few years for the
management of peritoneal disseminations of digestive and gynecological cancers …
management of peritoneal disseminations of digestive and gynecological cancers …
Electrical impedance spectroscopy for monitoring chemoresistance of cancer cells
LL Crowell, JS Yakisich, B Aufderheide, TNG Adams - Micromachines, 2020 - mdpi.com
Electrical impedance spectroscopy (EIS) is an electrokinetic method that allows for the
characterization of intrinsic dielectric properties of cells. EIS has emerged in the last decade …
characterization of intrinsic dielectric properties of cells. EIS has emerged in the last decade …
Vascularized microfluidic platforms to mimic the tumor microenvironment
Microfluidic technology has led to the development of advanced in vitro tumor platforms that
overcome the challenges of in vivo animal and in vitro two dimensional models. This paper …
overcome the challenges of in vivo animal and in vitro two dimensional models. This paper …
Microfluidic models of the human circulatory system: versatile platforms for exploring mechanobiology and disease modeling
N Nguyen, P Thurgood, NC Sekar, S Chen… - Biophysical …, 2021 - Springer
The human circulatory system is a marvelous fluidic system, which is very sensitive to
biophysical and biochemical cues. The current animal and cell culture models do not …
biophysical and biochemical cues. The current animal and cell culture models do not …