[HTML][HTML] A comprehensive review on recent advances in exosome isolation and characterization: Toward clinical applications

N Dilsiz - Translational oncology, 2024 - Elsevier
Exosomes are small, round vesicles in the 30 and 120 nm diameter range released by all
living cell types. Exosomes play many essential functions in intercellular communication and …

Tumor-derived systems as novel biomedical tools—turning the enemy into an ally

N Desai, P Katare, V Makwana, S Salave… - Biomaterials …, 2023 - spj.science.org
Cancer is a complex illness that presents significant challenges in its understanding and
treatment. The classic definition," a group of diseases characterized by the uncontrolled …

[HTML][HTML] Extracellular vesicles transport RNA between cells: Unraveling their dual role in diagnostics and therapeutics

Z Payandeh, B Tangruksa, J Synnergren… - Molecular Aspects of …, 2024 - Elsevier
Modern methods of molecular diagnostics and therapy have revolutionized the field of
medicine in recent years by providing more precise and effective tools for detecting and …

Micro-RNAs shuttled by extracellular vesicles secreted from mesenchymal stem cells dampen astrocyte pathological activation and support neuroprotection in in-vitro …

F Provenzano, S Nyberg, D Giunti, C Torazza, B Parodi… - Cells, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with no effective cure.
Astrocytes display a toxic phenotype in ALS and contribute to motoneuron (MN) …

Strategies for engineering of extracellular vesicles

AA Danilushkina, CC Emene, NA Barlev… - International journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are membrane vesicles released by cells into the extracellular
space. EVs mediate cell-to-cell communication through local and systemic transportation of …

The Regulation of Exosome Generation and Function in Physiological and Pathological Processes

Y Wang, T **ao, C Zhao, G Li - International Journal of Molecular …, 2023 - mdpi.com
Exosomes, a type of extracellular vesicle with a diameter of approximately 100 nm that is
secreted by all cells, regulate the phenotype and function of recipient cells by carrying …

[HTML][HTML] A brief review on recent advances in diagnostic and therapeutic applications of extracellular vesicles in cardiovascular disease

D Das, G Jothimani, A Banerjee, A Dey… - The international journal …, 2024 - Elsevier
Extracellular vesicles (EVs) are important mediators of intercellular communication within
the cardiovascular system, playing essential roles in physiological homeostasis and …

Biodelivery of therapeutic extracellular vesicles: should mononuclear phagocytes always be feared?

M Cieślik, K Bryniarski, K Nazimek - Frontiers in Cell and …, 2023 - frontiersin.org
At present, extracellular vesicles (EVs) are considered key candidates for cell-free therapies,
including treatment of allergic and autoimmune diseases. However, their therapeutic …

Standardized reporting of research on exosomes to ensure rigor and reproducibility

A Yadav, Y Xuan, CK Sen, S Ghatak - Advances in Wound Care, 2024 - liebertpub.com
Significance: The study of extracellular vesicles (EVs), especially exosomes, has unlocked
new avenues in understanding cellular communication and potential therapeutic …

The role and applications of extracellular vesicles in osteoporosis

F Fang, J Yang, J Wang, T Li, E Wang, D Zhang, X Liu… - Bone research, 2024 - nature.com
Osteoporosis is a widely observed condition characterized by the systemic deterioration of
bone mass and microarchitecture, which increases patient susceptibility to fragile fractures …