Mechanisms linking cerebrovascular dysfunction and tauopathy: Adding a layer of epiregulatory complexity
Intracellular accumulation of hyperphosphorylated misfolded tau proteins are found in many
neurodegenerative tauopathies, including Alzheimer's disease (AD). Tau pathology can …
neurodegenerative tauopathies, including Alzheimer's disease (AD). Tau pathology can …
Gene networks and systems biology in Alzheimer's disease: Insights from multi‐omics approaches
Despite numerous studies in the field of dementia and Alzheimer's disease (AD), a
comprehensive understanding of this devastating disease remains elusive. Bulk …
comprehensive understanding of this devastating disease remains elusive. Bulk …
Sex‐specific declines in cholinergic‐targeting tRNA fragments in the nucleus accumbens in Alzheimer's disease
Abstract Introduction Females with Alzheimer's disease (AD) suffer accelerated dementia
and loss of cholinergic neurons compared to males, but the underlying mechanisms are …
and loss of cholinergic neurons compared to males, but the underlying mechanisms are …
Neurodegenerative disorders: From clinicopathology convergence to systems biology divergence
Neurodegenerative diseases are multifactorial. This means that several genetic, epigenetic,
and environmental factors contribute to their emergence. Therefore, for the future …
and environmental factors contribute to their emergence. Therefore, for the future …
[HTML][HTML] Single-nucleus multi-omics identifies shared and distinct pathways in Pick's and Alzheimer's disease
The study of neurodegenerative diseases, particularly tauopathies like Pick's disease (PiD)
and Alzheimer's disease (AD), offers insights into the underlying regulatory mechanisms. By …
and Alzheimer's disease (AD), offers insights into the underlying regulatory mechanisms. By …
Identification of Autophagy-Related Candidate Genes in the Early Diagnosis of Alzheimer's Disease and Exploration of Potential Molecular Mechanisms
J Wang, X Huo, H Zhou, H Liu, X Li, N Lu, X Sun - Molecular Neurobiology, 2024 - Springer
This study aimed to identify autophagy-related candidate genes for the early diagnosis of
Alzheimer's disease (AD) and elucidate their potential molecular mechanisms. Differentially …
Alzheimer's disease (AD) and elucidate their potential molecular mechanisms. Differentially …
Drug resistance in breast cancer
N Madnoorkar, R Jain, R Sapate, GS Bhamra… - …, 2024 - journalsmededu.pl
Objective: The obstacle of resistance throughout breast cancer treatment leads to failure of
therapy and progress in the disease. Current developments in our knowledge of the …
therapy and progress in the disease. Current developments in our knowledge of the …
Diverse Mouse Models Reveal Genetic Context Controls the Molecular and Neural Landscape of the Aged and Alzheimer's Disease Brain
SE Heuer - 2024 - search.proquest.com
The predominance of age-related diseases such as Alzheimer's disease (AD) are projected
to double over the next several decades, which is attributed to the rapidly growing aging …
to double over the next several decades, which is attributed to the rapidly growing aging …