[HTML][HTML] Bacterial iron detoxification at the molecular level
JM Bradley, DA Svistunenko, MT Wilson… - Journal of Biological …, 2020 - Elsevier
Iron is an essential micronutrient, and, in the case of bacteria, its availability is commonly a
growth-limiting factor. However, correct functioning of cells requires that the labile pool of …
growth-limiting factor. However, correct functioning of cells requires that the labile pool of …
Dps is a universally conserved dual-action DNA-binding and ferritin protein
K Orban, SE Finkel - Journal of bacteriology, 2022 - journals.asm.org
The DNA-binding protein from starved cells, Dps, is a universally conserved prokaryotic
ferritin that, in many species, also binds DNA. Dps homologs have been identified in the vast …
ferritin that, in many species, also binds DNA. Dps homologs have been identified in the vast …
Dps functions as a key player in bacterial iron homeostasis
Iron plays a vital role in the maintenance of life, being central to various cellular processes,
from respiration to gene regulation. It is essential for iron to be stored in a nontoxic and …
from respiration to gene regulation. It is essential for iron to be stored in a nontoxic and …
Functionalization of protein crystals with metal ions, complexes and nanoparticles
S Abe, B Maity, T Ueno - Current opinion in chemical biology, 2018 - Elsevier
Highlights•Design and engineering of protein crystals with metal coordination.•Growth of
metal nanoclusters in engineered protein crystals and structures.•Creation of functional …
metal nanoclusters in engineered protein crystals and structures.•Creation of functional …
Miniferritins: Small multifunctional protein cages
The subject of this review article was first reported approximately three decades ago upon
the discovery of a starvation-inducible protein found tightly bound to chromosomal DNA in 3 …
the discovery of a starvation-inducible protein found tightly bound to chromosomal DNA in 3 …
[HTML][HTML] Structural insights into iron ions accumulation in Dps nanocage
Dps (DNA-binding protein from starved cells) is well known for the structural protection of
bacterial DNA by the formation of highly ordered intracellular assemblies under stress …
bacterial DNA by the formation of highly ordered intracellular assemblies under stress …
An overview of Dps: Dual acting nanovehicles in prokaryotes with DNA binding and ferroxidation properties
D NA binding p roteins under s tarvation (Dps) are proteins belonging to the ferritin family
with the capacity for DNA binding, in addition to iron storage and ferroxidation. Present only …
with the capacity for DNA binding, in addition to iron storage and ferroxidation. Present only …
Biochemical and structural characterization of a thermostable Dps protein with His‐type ferroxidase centers and outer metal‐binding sites
The DNA‐binding protein from starved cells (Dps) is found in a wide range of
microorganisms, and it has been well characterized. However, little is known about Dps …
microorganisms, and it has been well characterized. However, little is known about Dps …
Iron/iron oxide nanoparticles: advances in microbial fabrication, mechanism study, biomedical, and environmental applications
Microbially synthesized iron oxide nanoparticles (FeONPs) hold great potential for
biomedical, clinical, and environmental applications owing to their several unique features …
biomedical, clinical, and environmental applications owing to their several unique features …
Key carboxylate residues for iron transit through the prokaryotic ferritin SynFtn
JM Bradley, J Fair, AM Hemmings… - Microbiology, 2021 - microbiologyresearch.org
Ferritins are proteins forming 24meric rhombic dodecahedral cages that play a key role in
iron storage and detoxification in all cell types. Their function requires the transport of Fe2+ …
iron storage and detoxification in all cell types. Their function requires the transport of Fe2+ …